Salvadori B, Fariselli G, Saccozzi R
Tumori. 1976 Sep-Oct;62(5):529-35. doi: 10.1177/030089167606200507.
Of 100 cases of Paget's disease of the breast admitted to the National Career Institute of Milan from 1940 to 1974, 91 were statistically evaluated. They were divided in two groups according to presence or absence of a palpable nodule. The results of surgical treatment in terms of 5 and 10 year survival rates were 59 and 44%, respectively, with a median survival of 9 years. For the two separate subgroups, those with a palpable nodule were 38 and 22% for 5 and 10 years, respectively, while those without a palpable nodule were 92 and 82% for 5 and 10 years, respectively. For the two groups the median survival was 3.6 and 16.4 years, respectively. The extent of surgery should be dependent on the presence of absence of palpable nodules under the nipple. For the two groups (with and without) extended radical mastectomy and the Patey-Dawson mastectomy are recommended.
1940年至1974年期间，米兰国家职业研究所收治了100例乳腺佩吉特病患者，其中91例进行了统计学评估。根据是否可触及结节将患者分为两组。手术治疗的5年和10年生存率分别为59%和44%，中位生存期为9年。对于两个独立的亚组，有可触及结节的患者5年和10年生存率分别为38%和22%，无可触及结节的患者5年和10年生存率分别为92%和82%。两组的中位生存期分别为3.6年和16.4年。手术范围应取决于乳头下是否存在可触及结节。对于这两组患者（有和无结节），建议行扩大根治性乳房切除术和佩蒂-道森乳房切除术。
