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源参数对使用蒙特卡罗方法计算的大野电子束轮廓的影响。

Influence of source parameters on large-field electron beam profiles calculated using Monte Carlo methods.

作者信息

Weinberg Rebecca, Antolak John A, Starkschall George, Kudchadker Rajat J, White R Allen, Hogstrom Kenneth R

机构信息

Department of Radiation Physics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

出版信息

Phys Med Biol. 2009 Jan 7;54(1):105-16. doi: 10.1088/0031-9155/54/1/007. Epub 2008 Dec 10.

DOI:10.1088/0031-9155/54/1/007
PMID:19075360
Abstract

The purpose of this paper was to study the source model for a Monte Carlo simulation of electron beams from a medical linear accelerator. In a prior study, a non-divergent Gaussian source with a full-width at half-maximum (FWHM) of 0.15 cm was successful in predicting relative dose distributions for electron beams with applicators. However, for large fields with the applicator removed, discrepancies were found between measured and calculated profiles, particularly in the shoulder region. In this work, the source was changed to a divergent Gaussian spatial distribution and the FWHM parameter was varied to produce better agreement with measured data. The influence of the FWHM source parameter on profiles was observed at multiple locations in the simulation geometry including in-air fluence profiles at a 95 cm source-to-surface distance (SSD), percent depth dose profiles and off-axis profiles (OARs) in a water phantom for two SSDs, 80 and 100 cm. For a 6 MeV 40 x 40 cm(2) OAR profile, discrepancies in the shoulder region were reduced from 15% to 4% using a FWHM value of 0.45 cm. The optimal FWHM values for the other energies were 0.45 cm for 9 MeV, 0.22 for 12 MeV, 0.25 for 16 MeV and 0.2 cm for 20 MeV. Although this range of values was larger than measured focal spot sizes reported by other researchers, using the increased FWHM values improved the fit at most locations in the simulation geometry, giving confidence that the model could be used with a variety of SSDs and field sizes.

摘要

本文的目的是研究用于医学直线加速器电子束蒙特卡罗模拟的源模型。在先前的一项研究中,半高宽(FWHM)为0.15厘米的非发散高斯源成功地预测了带有施源器的电子束的相对剂量分布。然而,对于移除施源器的大射野,在测量和计算的剂量分布曲线之间发现了差异,特别是在剂量坪区。在这项工作中,将源改为发散高斯空间分布,并改变FWHM参数以使其与测量数据更好地吻合。在模拟几何结构的多个位置观察了FWHM源参数对剂量分布曲线的影响,包括在源皮距(SSD)为95厘米时的空气中注量分布曲线、在水模体中两个SSD(80厘米和100厘米)下的百分深度剂量分布曲线和离轴剂量分布曲线(OARs)。对于6兆电子伏40×40平方厘米的OAR剂量分布曲线,使用0.45厘米的FWHM值时,剂量坪区的差异从15%降低到了4%。其他能量的最佳FWHM值分别为:9兆电子伏时为0.45厘米,12兆电子伏时为0.22厘米,16兆电子伏时为0.25厘米,20兆电子伏时为(此处原文有误,可能参考内容为0.20cm )0.2厘米。尽管这个值的范围比其他研究人员报告的测量焦斑尺寸要大,但使用增加的FWHM值改善了模拟几何结构中大多数位置的拟合,这使得我们相信该模型可用于各种SSD和射野尺寸。

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