Martín Escribano P, Díaz de Atauri M J, Gómez Sánchez M A
Department of Pneumology, Hospital 12 de Octubre, Madrid, Spain.
Chest. 1991 Aug;100(2):336-9. doi: 10.1378/chest.100.2.336.
We studied a random sample of 436 subjects with TOS aged 18 to 60 years, to assess the prevalence of respiratory involvement four years after onset of the syndrome. Clinical evaluation together with chest roentgenograms, electrocardiogram and functional respiratory tests were carried out. Respiratory involvement occurred in 390 (89.4 percent) individuals and was the most common abnormality detected, followed by neurological disorders in 289 (66.3 percent), osteoarticular symptoms in 171 (39.2 percent), psychiatric disorders in 96 (22 percent), hepatic involvement in 91 (20.9 percent), and sclerodermatous sequelae in 89 (20.4 percent). Among patients with respiratory involvement, dyspnea and cough were the most common complaints. Decreased VC was observed in 151 (34.6 percent) patients and reduced transfer factor of CO in 95 (21.8 percent) patients. Airway obstruction and alveolar hypoventilation were observed only in nine (2.1 percent) patients. Six (1.4 percent) patients suffered from pulmonary artery hypertension.
我们对436名年龄在18至60岁之间的胸廓出口综合征（TOS）患者进行了随机抽样研究，以评估该综合征发病四年后呼吸系统受累的患病率。我们进行了临床评估，并拍摄了胸部X光片、心电图以及进行了呼吸功能测试。390名（89.4%）个体出现了呼吸系统受累，这是检测到的最常见异常，其次是289名（66.3%）出现神经功能障碍，171名（39.2%）出现骨关节症状，96名（22%）出现精神障碍，91名（20.9%）出现肝脏受累，89名（20.4%）出现硬皮病后遗症。在呼吸系统受累的患者中，呼吸困难和咳嗽是最常见的症状。151名（34.6%）患者观察到肺活量（VC）降低，95名（21.8%）患者观察到一氧化碳转运因子降低。仅9名（2.1%）患者观察到气道阻塞和肺泡通气不足。6名（1.4%）患者患有肺动脉高压。
