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贲门失弛缓症气囊扩张术前后临床症状与影像学表现的相关性

[Correlation between clinical symptoms and radiologic findings before and after pneumatic balloon dilatation for achalasia].

作者信息

Moon Jong Tae, Jung In Su, Kim Young Shin, Cho Seung Hyun, Park Hyojin, Lee Sang In

机构信息

Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Korean J Gastroenterol. 2008 Jul;52(1):16-20.

Abstract

BACKGROUND/AIMS: We investigated the risk factors for short-term recurrence and analyzed the correlation between subjective clinical symtoms and objective radiological findings in patients with achalasia undergoing pneumatic balloon dilatation.

METHODS

Twenty patients who were treated by pneumatic balloon dilatation were enrolled. We compared prospectively various indices before and after the treatment as follows: 1) Eckardt symptom score and dysphagia grade, 2) The ratio of the maximal width in mid-esophageal lumen to the minimal width in distal esophagus around lower esophageal sphincter, and 3) the percentage of maximum activity retained in the esophagus at 30 seconds and T in esophageal scan two days after the treatment.

RESULTS

  1. Clinical indices and radiologic indices significantly improved after pneumatic dilatation. 2) There was no significant correlation between the clinical indices and the radiologic indices before and after the treatment. 3) The difference percentage of clinical indices did not show significant correlation with the difference percentage of the radiologic indices. 4) Compared to the group above 20% in the difference percentage of 30 second residual fraction, the one below 20% had a four-fold risk in short-term recurrence.

CONCLUSIONS

Clinical symptoms and radiologic indices significantly improve after pneumatic dilatation but have no significant correlation to each other. The group below 20% in the difference percentage of 30 second residual fraction has a high risk of recurrence and may need careful examination and early repeated pneumatic dilation.

摘要

背景/目的:我们研究了贲门失弛缓症患者接受气囊扩张术后短期复发的危险因素,并分析了主观临床症状与客观影像学表现之间的相关性。

方法

纳入20例接受气囊扩张术治疗的患者。我们前瞻性地比较了治疗前后的各项指标:1)埃卡德特症状评分和吞咽困难分级;2)食管中段管腔最大宽度与食管下括约肌周围远端食管最小宽度之比;3)治疗后两天食管扫描中30秒时食管保留的最大活性百分比和T值。

结果

1)气囊扩张术后临床指标和影像学指标显著改善。2)治疗前后临床指标与影像学指标之间无显著相关性。3)临床指标的差异百分比与影像学指标的差异百分比无显著相关性。4)与30秒残余分数差异百分比高于20%的组相比,低于20%的组短期复发风险高四倍。

结论

气囊扩张术后临床症状和影像学指标显著改善,但彼此无显著相关性。30秒残余分数差异百分比低于20%的组复发风险高,可能需要仔细检查并尽早重复气囊扩张。

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