Griffin Xavier L, Costello Isabel, Costa Matthew L
Warwick Orthopaedics, Clinical Sciences Research Institute, Coventry, United Kingdom.
J Trauma. 2008 Dec;65(6):1446-52. doi: 10.1097/TA.0b013e318185e222.
The aim of this study was to review the evidence regarding the use of low intensity pulsed ultrasound (LIPUS) in the management of acute long bone fractures.
Systematic review of Medline, Embase, and CINAHL databases. Further published studies were retrieved by hand searching bibliographies of relevant articles. Retrieved studies were limited to English-language studies published since 1956. Retrieved studies were excluded from review using the following criteria: case reports, exclusively pathologic fractures, treatment of therapeutic osteotomies and arthrodesis, initiation of ultrasound therapy after the first month following injury, no reporting of assessment of time to fracture healing, cellular studies, and nonclinical articles. Studies were reviewed independently by two reviewers using the CONSORT score. No statistical analysis was performed as the data from the studies were not suitable for pooled analysis.
Seven randomized controlled trials and two meta-analyses were retrieved using the search strategy.
The literature supports the use of LIPUS in the treatment of acute fractures treated with plaster immobilization.
本研究的目的是回顾关于低强度脉冲超声（LIPUS）在急性长骨骨折治疗中应用的证据。
对Medline、Embase和CINAHL数据库进行系统综述。通过手工检索相关文章的参考文献获取更多已发表的研究。检索到的研究限于1956年以来发表的英文研究。使用以下标准将检索到的研究排除在综述之外：病例报告、单纯病理性骨折、治疗性截骨术和关节融合术的治疗、受伤后第一个月后开始超声治疗、未报告骨折愈合时间评估、细胞研究和非临床文章。两名审阅者使用CONSORT评分独立对研究进行审阅。由于研究数据不适合进行汇总分析，因此未进行统计分析。
使用该检索策略检索到七项随机对照试验和两项荟萃分析。
文献支持LIPUS用于石膏固定治疗的急性骨折。
