Fisher Justin, Parkinson Kari, Kothari Milind J
From the Division of Neurology, Pennsylvania State University, College of Medicine, Hershey, Pennsylvania.
J Clin Neuromuscul Dis. 2003 Mar;4(3):105-8. doi: 10.1097/00131402-200303000-00001.
It is well known that patients with a chronic medical illness experience major depression at a higher rate than the general population. The purpose of this study was to determine the frequency of depression among patients with myasthenia gravis (MG) who were referred to a Muscular Dystrophy Association clinic. Forty-five patients with a diagnosis of MG were evaluated with a self-administered survey regarding various typical somatic and psychologic symptoms of depression (the Beck Depression Inventory [BDI]) and then scored according to the BDI guidelines. Thirty-three percent of these patients generated scores suggestive of depression (24% were categorized as mildly depressed, 7% as moderately depressed, and 2% as severely depressed). These results suggest that patients with MG patients experience depression at a higher rate than the general population and at a similar rate as patients with other chronic illnesses.
众所周知，患有慢性疾病的患者患重度抑郁症的几率高于普通人群。本研究的目的是确定被转诊至肌肉萎缩症协会诊所的重症肌无力（MG）患者中抑郁症的发生率。45名被诊断为MG的患者通过一份关于各种典型的抑郁躯体和心理症状的自我管理调查问卷（贝克抑郁量表[BDI]）进行评估，然后根据BDI指南进行评分。这些患者中有33%的得分表明患有抑郁症（24%被归类为轻度抑郁，7%为中度抑郁，2%为重度抑郁）。这些结果表明，MG患者患抑郁症的几率高于普通人群，且与其他慢性疾病患者的发生率相似。
