Poulsen Mette Buch, Bojsen-Moller Marie, Jakobsen Johannes, Andersen Henning
From the Departments of *Neurology and daggerNeuropathology, Aarhus University Hospital, Aarhus, Denmark.
J Clin Neuromuscul Dis. 2005 Sep;7(1):36-41. doi: 10.1097/01.cnd.0000177424.88495.53.
Clinical usefulness and safety of percutaneous conchotome biopsy of the deltoid muscle and of the quadriceps muscle was compared in patients suspected to have a neuromuscular disorder. In 121 samples from the quadriceps muscle and in 39 samples from the deltoid muscle, the quantity of muscle fibers was equal and the fraction of biopsies resulting in a specific diagnosis was similar (50% and 56%, respectively). Also, biopsy from the 2 locations resulted in the same distribution of neurogenic, inflammatory, and myopathic disorders. After quadriceps muscle biopsy, 2 patients developed vasovagal syncopes and one patient a local hematoma, whereas no complications occurred in the patients subjected to deltoid muscle biopsy. We conclude that biopsy from the deltoid muscle is clinically as useful and safe as biopsy from the quadriceps muscle.
在疑似患有神经肌肉疾病的患者中，对三角肌和股四头肌经皮肌刀活检的临床实用性和安全性进行了比较。在121例股四头肌样本和39例三角肌样本中，肌纤维数量相等，导致明确诊断的活检比例相似（分别为50%和56%）。此外，从这两个部位进行活检导致的神经源性、炎症性和肌病性疾病分布相同。股四头肌活检后，2例患者发生血管迷走性晕厥，1例患者出现局部血肿，而三角肌活检患者未发生并发症。我们得出结论，三角肌活检在临床上与股四头肌活检一样有用且安全。
