Wang Xin, Turunen Brandon J, Leighty Matthew W, Georg Gunda I
Department of Medicinal Chemistry and Center for Methodology and Library Development, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, Kansas 66045, USA.
Tetrahedron Lett. 2007 Dec 10;48(50):8811-8814. doi: 10.1016/j.tetlet.2007.10.078.
A systematic study of α-iodination and subsequent Suzuki-Miyaura couplings between non-attenuated enaminones and a wide range of aromatic boronic acids is reported. The microwave-assisted variant of this transformation furnished the α-arylenaminones in significantly shorter reaction times and slightly improved yields as compared to conventional heating.
报道了对未衰减烯胺酮与多种芳基硼酸之间的α-碘化及随后的铃木-宫浦偶联反应的系统研究。与传统加热相比，该转化反应的微波辅助变体能够在显著更短的反应时间内得到α-芳基烯胺酮，产率也略有提高。
