Draganova-Tacheva Rossitza Anguelova, Khurana Jasvirs S, Huang Yajue, Hernandez Enrique, Zhang Xinmin
Departments of Pathology and Laboratory Medicine1 and Gynecologic Oncology2, Temple University Hospital, Philadelphia, Pennsylvania, USA.
Int J Clin Exp Pathol. 2009;2(3):304-9. Epub 2008 Nov 8.
Large cell neuroendocrine carcinoma (LCNEC) of the ovary is a rare entity and is frequently associated with ovarian surface epithelial tumors. However, its association with serous carcinoma has only been described recently in one case. We report another case of such with mucin production in a 68-year old woman. Immunohistochemistry and mucicarmine stain confirmed the diagnosis. Its clinicopathologic association is discussed and the literature is reviewed.
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