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[醋酸盐与碳酸氢盐血液透析治疗儿童慢性尿毒症的对比研究]

[Comparative study of acetate and bicarbonate hemodialysis in children with chronic uremia].

作者信息

Dobos E, Túri S, Sztriha L

机构信息

Szent-Györgyi Albert Orvostudományi Egyetem, Szeged.

出版信息

Orv Hetil. 1991 Aug 11;132(32):1749-54.

PMID:1908071
Abstract

Comparative studies on 5 children suffering from chronic uremia were performed regarding the efficacy of acetate and bicarbonate hemodialysis. Clinical symptoms, acid-base and blood gas analysis, serum osmolality, blood pressure and EEG were examined. On authors experience the patients tolerated better the bicarbonate dialysis. Laboratory data and blood pressure were found to be closer to the normal values too. The abnormality of EEG made after bicarbonate dialysis were not so expressed than that of acetate dialysis. On the basis of this examinations the authors suggest the bicarbonate hemodialysis in uremic patients with severe cardiovascular and/or neurological complications.

摘要

对5名慢性尿毒症患儿进行了醋酸盐和碳酸氢盐血液透析疗效的比较研究。检查了临床症状、酸碱及血气分析、血清渗透压、血压和脑电图。根据作者的经验,患者对碳酸氢盐透析的耐受性更好。实验室数据和血压也更接近正常值。碳酸氢盐透析后脑电图的异常表现不如醋酸盐透析明显。基于这些检查,作者建议对患有严重心血管和/或神经并发症的尿毒症患者采用碳酸氢盐血液透析。

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