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[嗜肺军团菌与梨形四膜虫这种纤毛原生动物相互作用的超微结构特征]

[The ultrastructural characteristics of the interaction of Legionella pneumophila with the infusorian protozoon Tetrahymena pyriformis].

作者信息

Popov V L, Konstantinova N D, Merkurov A E, Tartakovskiĭ I S, Litvin V Iu

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1991 Mar(3):5-10.

PMID:1908167
Abstract

In this work the morphological features of the interaction of L. pneumophila virulent strain and T. pyriformis have been studied on the submicroscopic level in the time course of the process. The study has shown the process of the destruction of the bacterial population and the penetration of individual intact Legionella cells from the phagosome into the endoplasm of T. pyriformis after 6-9 hours of interaction in the form of the budding of the phagosome and further multiplication of Legionella in the endoplasm. As revealed in this study, T. pyriformis have two types of phagosomes characterized by different variants of the destruction of Legionella. In T. pyriformis lysosomes-like granules, mitochondria and the granular endoplasmatic network take part in the process of interaction. The process of interaction has been found to end by day 7 in the death of all protozoal cells taking part in interaction.

摘要

在这项工作中,已在亚微观层面研究了嗜肺军团菌强毒株与梨形四膜虫相互作用过程中的形态学特征。研究表明,在相互作用6 - 9小时后,细菌群体出现破坏过程,单个完整的军团菌细胞以吞噬体出芽的形式从吞噬体进入梨形四膜虫的内质,随后军团菌在内质中进一步繁殖。如本研究所示,梨形四膜虫有两种类型的吞噬体,其特征在于军团菌破坏的不同变体。在梨形四膜虫中,类似溶酶体的颗粒、线粒体和颗粒状内质网参与了相互作用过程。已发现相互作用过程在第7天结束,所有参与相互作用的原生动物细胞均死亡。

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