Section of Infectious Diseases, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Diagn Microbiol Infect Dis. 2010 Jan;66(1):111-5. doi: 10.1016/j.diagmicrobio.2008.10.003. Epub 2008 Dec 10.
A case of bacteremia caused by Pediococcus acidilactici occurring in a patient with metastatic adenocarcinoma of the gallbladder is described. The bacteremia persisted despite an antimicrobial regimen of vancomycin, ciprofloxacin, metronidazole, and caspofungin. Within 36 h of switching the vancomycin to daptomycin (6 mg/kg per day), the bacteremia resolved and the patient improved clinically. Previous reports of human pediococcal infection are also reviewed.
现报道 1 例转移性胆囊腺癌患者发生的由乳酸片球菌引起的菌血症。尽管采用万古霉素、环丙沙星、甲硝唑和卡泊芬净的抗菌治疗方案，但菌血症仍持续存在。将万古霉素换用达托霉素（每天 6mg/kg）后 36 h 内，菌血症得到解决，患者的临床状况得到改善。还回顾了以前关于人类肠球菌感染的报告。
