Michalopoulos Nick, Arampatzi Stergiani, Papavramidis Theodossis S, Kotidis Efstathios, Laskou Styliani, Papavramidis Spiros T
3rd Department of Surgery, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece.
Int J Surg Case Rep. 2013;4(3):286-9. doi: 10.1016/j.ijscr.2012.12.008. Epub 2013 Jan 5.
Soft tissue necrotizing infections are a significant cause of morbidity and mortality. The aim of this study is to present a patient with necrotizing infection of abdominal wall resulting from the rupture of a retroperitoneal stromal tumor.
We present a 60-year-old Caucasian male patient with necrotizing infection of abdominal wall secondary to the rupture of a retroperitoneal stromal tumor. The patient was initially treated with debridement and fasciotomy of the anterior abdominal wall. Laparotomy revealed purulent peritonitis caused by infiltration and rupture of the splenic flexure by the tumor. Despite prompt intervention the patient died 19 days later. The isolated microorganism causing the infection was the rarely identified as cause of infections in humans Pediococcus sp., a gram-positive, catalase-negative coccus.
Necrotizing infections of abdominal wall are usually secondary either to perineal or to intra-abdominal infections. Gastrointestinal stromal cell tumors could be rarely complicated with perforation and abscess formation. In our case, the infiltrated by the extra-gastrointestinal stromal cell tumor ruptured colon was the source of the infection. The pediococci are rarely isolated as the cause of severe septicemia.
Ruptured retroperitoneal stromal cell tumors are extremely rare cause of necrotizing fasciitis, and before this case, Pediococcus sp. has never been isolated as the responsible agent.
软组织坏死性感染是发病和死亡的重要原因。本研究的目的是报告一例因腹膜后间质瘤破裂导致腹壁坏死性感染的患者。
我们报告一名60岁的白种男性患者,因腹膜后间质瘤破裂继发腹壁坏死性感染。患者最初接受了前腹壁清创术和筋膜切开术。剖腹探查发现肿瘤浸润并破裂脾曲导致脓性腹膜炎。尽管及时进行了干预,患者仍在19天后死亡。引起感染的分离微生物是罕见的人类感染病原菌嗜热四联球菌,一种革兰氏阳性、过氧化氢酶阴性球菌。
腹壁坏死性感染通常继发于会阴或腹腔内感染。胃肠道间质细胞瘤很少并发穿孔和脓肿形成。在我们的病例中,胃肠道外间质细胞瘤浸润破裂的结肠是感染源。嗜热四联球菌很少作为严重败血症的病因被分离出来。
腹膜后间质细胞瘤破裂是坏死性筋膜炎极为罕见的病因,在此病例之前,嗜热四联球菌从未被分离为致病因子。