Rijal Keshab, Chow Christine S
Department of Chemistry, Wayne State University, Detroit, Michigan, 48202, USA.
Chem Commun (Camb). 2009 Jan 7(1):107-9. doi: 10.1039/b816633a. Epub 2008 Nov 10.
In this study, cisplatin, the well-known anticancer drug, was used to probe accessible purine residues in E. coli 16S ribosomal RNA (rRNA), free or in the context of 30S subunits or 70S ribosomes, both in vitro and in vivo.
在本研究中,著名的抗癌药物顺铂被用于探测大肠杆菌16S核糖体RNA(rRNA)中可及的嘌呤残基,无论是游离状态,还是处于30S亚基或70S核糖体环境中,均在体外和体内进行了探测。