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一种基于DNA构象转换和金纳米颗粒聚集的简单灵敏的比色pH计。

A simple and sensitive colorimetric pH meter based on DNA conformational switch and gold nanoparticle aggregation.

作者信息

Chen Cuie, Song Guangtao, Ren Jinsong, Qu Xiaogang

机构信息

State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022.

出版信息

Chem Commun (Camb). 2008 Dec 14(46):6149-51. doi: 10.1039/b812660g. Epub 2008 Oct 14.

Abstract

A simple and rapid colorimetric pH meter has been developed based on the conformational switch of i-motif DNA and non-crosslinking AuNP aggregation, the average accuracy of the nano-meter was found to be +/-0.04 pH unit across the physiological operating range.

摘要

基于i-基序DNA的构象转换和非交联金纳米颗粒聚集,开发了一种简单快速的比色pH计,发现在生理操作范围内,该纳米计的平均准确度为±0.04 pH单位。

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