开发用于疾病诊断的纳米传感器的不同方法。

Arndt Nina, Tran Huong D N, Zhang Run, Xu Zhi Ping, Ta Hang T

Queensland Micro- and Nanotechnology Centre Griffith University Brisbane Queensland 4111 Australia.

Australian Institute for Bioengineering and Nanotechnology the University of Queensland Brisbane Queensland 4072 Australia.

Adv Sci (Weinh). 2020 Oct 28;7(24):2001476. doi: 10.1002/advs.202001476. eCollection 2020 Dec.

The success of clinical treatments is highly dependent on early detection and much research has been conducted to develop fast, efficient, and precise methods for this reason. Conventional methods relying on nonspecific and targeting probes are being outpaced by so-called nanosensors. Over the last two decades a variety of activatable sensors have been engineered, with a great diversity concerning the operating principle. Therefore, this review delineates the achievements made in the development of nanosensors designed for diagnosis of diseases.

临床治疗的成功高度依赖于早期检测，因此已经开展了许多研究来开发快速、高效和精确的检测方法。依赖非特异性和靶向探针的传统方法正被所谓的纳米传感器超越。在过去二十年中，已经设计出了多种可激活传感器，其工作原理具有很大的多样性。因此，本综述阐述了在用于疾病诊断的纳米传感器开发方面所取得的成就。