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接受非体外循环冠状动脉搭桥术的糖尿病患者中,双骨架化胸廓内动脉与双传统胸廓内动脉的比较

Double skeletonized internal thoracic artery vs. double conventional internal thoracic artery in diabetic patients submitted to OPCAB.

作者信息

Milani Rodrigo, Brofman Paulo Roberto, Guimarães Maximiliano, Barboza Laura, Tchaick Rodrigo Mezzalira, Meister Filho Hugo, Baggio Thales, Maia Francisco

机构信息

PUC/PR, Curitiba, PR, Brasil.

出版信息

Rev Bras Cir Cardiovasc. 2008 Jul-Sep;23(3):351-7. doi: 10.1590/s0102-76382008000300011.

DOI:10.1590/s0102-76382008000300011
PMID:19082323
Abstract

OBJECTIVE

To evaluate the influence of the technique used in the dissection of thoracic arteries in the evolution of diabetic patients submitted to OPCAB.

METHODS

Seventy diabetic patients submitted to OPCAB using bilateral thoracic arteries were evaluated. In Group A, thoracic arteries were dissected as a pedicle, while in Group B they were skeletonized.

RESULTS

The mean age of patients in Group A was 52.14 +/- 7.35 years old versus 55.71 +/- 8.1 years for Group B (p=0.057). In Group A, six patients (17.1%) were insulin dependent against nine (25.7%) in Group B (p = 0.561). The EUROSCORE was 3.97 +/- 2.49 for Group A opposed to 4.14 +/- 3.06 for Group B (p = 0.879). The number of distal anastomoses in Group A was 3 +/- 0.77 versus 3.03 +/- 0.89 in Group B (p = 0.981). Three patients (8.57%) from Group A presented with mediastinitis. Insulin dependence was the only significant risk factor (p=0.008) for mediastinitis. In this group the use of skeletonized internal thoracic arteries significantly decreased the incidence of mediastinitis (p = 0.044).

CONCLUSION

The incidence of mediastinitis was lower in the group for which mammary arteries were dissected using skeletonization. Among insulin-dependent diabetics, 50% of the patients from the group in which the pedicled internal thoracic artery was utilized presented with mediastinitis; the utilization of skeletonized internal thoracic arteries significantly decreases the incidence of mediastinitis.

摘要

目的

评估在接受非体外循环冠状动脉搭桥术(OPCAB)的糖尿病患者中,胸段动脉解剖技术对其病情演变的影响。

方法

对70例使用双侧胸段动脉进行OPCAB的糖尿病患者进行评估。A组将胸段动脉作为蒂进行解剖,而B组则对其进行骨骼化处理。

结果

A组患者的平均年龄为52.14±7.35岁,B组为55.71±8.1岁(p=0.057)。A组有6例患者(17.1%)依赖胰岛素,B组有9例(25.7%)(p = 0.561)。A组的欧洲心脏手术风险评估系统(EUROSCORE)评分为3.97±2.49,B组为4.14±3.06(p = 0.879)。A组的远端吻合口数量为3±0.77,B组为3.03±0.89(p = 0.981)。A组有3例患者(8.57%)发生纵隔炎。胰岛素依赖是纵隔炎的唯一显著危险因素(p=0.008)。在该组中,使用骨骼化的胸廓内动脉可显著降低纵隔炎的发生率(p = 0.044)。

结论

采用骨骼化方法解剖乳内动脉的组中纵隔炎的发生率较低。在依赖胰岛素治疗的糖尿病患者中,使用带蒂胸廓内动脉的组中有50%的患者发生纵隔炎;使用骨骼化的胸廓内动脉可显著降低纵隔炎的发生率。

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J Cardiothorac Surg. 2019 Sep 9;14(1):162. doi: 10.1186/s13019-019-0985-9.
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Can the onset of heart failure be delayed by treating diabetic cardiomyopathy?通过治疗糖尿病性心肌病能否延缓心力衰竭的发作?
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Topical vasodilator response in skeletonized internal mammary artery: Is there really a difference?
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