Toyama Carlos, da Costa Leite Claudia, Filho Iulo Sérgio Baraúna, de Brito Neto Rubens Vuono, Bento Ricardo Fereira, Cerri Giovanni Guido, Gebrim Eloisa Maria Melo Santiago
Specialist, MD, researcher.
Associate Professor at FMUSP, Head of the Magnetic Resonance Sector at Fundação Faculdade de Medicina.
Braz J Otorhinolaryngol. 2008 Sep-Oct;74(5):693-696. doi: 10.1016/S1808-8694(15)31378-1.
Conventional CT and MRI scans have low specificity when it comes to differentiating granulation tissue from relapsing cholesteatoma.
this paper aims to analyze the use of DWI and delayed post-contrast T1-weighed imaging in the detection of recurring cholesteatomas.
this is a cross-sectional prospective study that looked at 17 cholesteatoma patients postoperatively. All patients underwent diffusion magnetic resonance imaging at 1.5T, T1, T2, and delayed post-contrast T1 and images were produced from both coronal and axial planes. Two radiologists assessed the images and decided consensually that the presence of hyperintensive signal in DWI on T2, iso/hypointensive signal on T1, and absence of contrast uptake were indicative of relapsing cholesteatoma. Surgical review findings were compared to DWI scans.
eleven of the twelve cases of recurring cholesteatoma presented hyperintensive signal in the DWI scans. None of the patients with granulation tissue in the surgical wound presented hyperintensive signal in the DWI scans. A patient with an abscess in the internal acoustic meatus also presented a hyperintensive signal in the DWI scans. Sensibility, specificity, positive predictive value and negative predictive value were 91.6%, 60.0%, 84.6%, and 75.0%, respectively.
DWI combined with delayed post-contrast T1 SE sequence proved to be useful in the differential diagnosis of granulation tissue and recurring cholesteatoma.
在区分肉芽组织与复发性胆脂瘤方面,传统CT和MRI扫描的特异性较低。
本文旨在分析弥散加权成像(DWI)和延迟增强T1加权成像在复发性胆脂瘤检测中的应用。
这是一项横断面前瞻性研究,观察了17例胆脂瘤患者术后情况。所有患者均接受1.5T的弥散磁共振成像、T1、T2以及延迟增强T1成像,图像采集于冠状面和轴位。两名放射科医生对图像进行评估,并达成共识,即DWI上的高信号、T2上的等/低信号以及无强化表现提示复发性胆脂瘤。将手术复查结果与DWI扫描结果进行比较。
12例复发性胆脂瘤中有11例在DWI扫描中表现为高信号。手术伤口有肉芽组织的患者在DWI扫描中均未表现出高信号。一名内耳道有脓肿的患者在DWI扫描中也表现为高信号。灵敏度、特异性、阳性预测值和阴性预测值分别为91.6%、60.0%、84.6%和75.0%。
DWI联合延迟增强T1 SE序列在肉芽组织和复发性胆脂瘤的鉴别诊断中被证明是有用的。