Brundel Bianca J J M, Melnyk Peter, Rivard Lena, Nattel Stanley
Research Center, Montreal Heart Institute and University of Montreal, QC, Canada; Department of Radiation and Stress Cell Biology, University of Groningen, The Netherlands.
J Vet Cardiol. 2005 Nov;7(2):121-9. doi: 10.1016/j.jvc.2005.07.001. Epub 2005 Oct 17.
Atrial fibrillation (AF) occurs in dogs in a number of settings, the most common of which is congestive heart failure. This paper reviews what is known about the pathology of AF in dogs, as well as its clinical relevance. We begin by discussing several experimental AF paradigms in dogs, the associated pathology, and its relevance to AF mechanisms. We then discuss clinical AF in dogs and its relationship to experimental pathology. Finally, we conclude by assessing the potential therapeutic relevance of understanding AF-related pathology in dogs, as well as its potential to have practical applications in the future.
心房颤动(AF)在多种情况下会发生于犬类,其中最常见的是充血性心力衰竭。本文综述了关于犬类AF病理学的已知信息及其临床相关性。我们首先讨论犬类的几种实验性AF模型、相关病理学及其与AF机制的相关性。然后我们讨论犬类的临床AF及其与实验病理学的关系。最后,我们通过评估了解犬类AF相关病理学的潜在治疗相关性及其未来实际应用的潜力来得出结论。