Donofrio Lisa M
Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA.
Aesthet Surg J. 2008 Nov-Dec;28(6):681-7. doi: 10.1016/j.asj.2008.09.003.
According to the author, autologous fat transplantation is an ideal technique to correct facial atrophy, providing a stable and potentially long lasting alternative to "off the shelf" fillers. Structural augmentation with fat involves multilayer blunt fat infiltration designed around concepts of volume expansion and resultant tissue shifting. The author has found that retention varies in different parts of the face and fat seems to "take" best in areas in which fat atrophy is the problem, such as in the cheek, periorbital area, and mandible. When fat is being used to replace bony remodeling or mucosal atrophy (both occur in the perioral area), retention can be unpredictable.
据作者称，自体脂肪移植是矫正面部萎缩的理想技术，为“现成的”填充剂提供了一种稳定且可能持久的替代方案。脂肪的结构性填充涉及围绕体积扩张和由此产生的组织移位概念设计的多层钝性脂肪浸润。作者发现，面部不同部位的脂肪留存情况各异，脂肪似乎在存在脂肪萎缩问题的区域（如脸颊、眶周区域和下颌骨）留存效果最佳。当使用脂肪来替代骨重塑或黏膜萎缩（两者均发生在口周区域）时，脂肪留存情况可能难以预测。
