Wetterau Meredith, Szpalski Caroline, Hazen Alexes, Warren Stephen M
Institute of Reconstructive Plastic Surgery, New York University School of Medicine, New York, New York 10016, USA.
J Craniofac Surg. 2012 Jan;23(1):315-8. doi: 10.1097/SCS.0b013e318241e1de.
There is tremendous interest in autologous fat grafting for the management of soft tissue volume deficiencies, treatment of cutaneous injuries, and regeneration of missing parts. Given its relative abundance and proximity to the surface of the skin, adipose tissue seems an excellent choice for the treatment of both congenital and acquired soft tissue defects, but the mesenchymal stem cells contained within the fat may provide unexpected opportunities for tissue replacement and repair. Although adipose transfer has been successfully used for reconstructive purposes since the end of the 19th century, numerous controversies about adipose harvesting, processing, delivery, survival, and efficacy still persist today. The purpose of this article was to highlight current practices, areas of controversy, and near-term future applications of fat grafting for reconstruction of the face.
自体脂肪移植在软组织容量不足的管理、皮肤损伤的治疗以及缺失部位的再生方面备受关注。鉴于脂肪组织相对丰富且靠近皮肤表面，它似乎是治疗先天性和后天性软组织缺损的理想选择，但脂肪中所含的间充质干细胞可能为组织替代和修复提供意想不到的机会。尽管自19世纪末以来脂肪移植已成功用于重建目的，但关于脂肪采集、处理、输送、存活和疗效的诸多争议至今仍然存在。本文旨在强调目前面部脂肪移植重建的实践、争议领域及近期的应用前景。
