Grinnell Frederick
Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX 75390-9039, USA.
J Bodyw Mov Ther. 2008 Jul;12(3):191-3. doi: 10.1016/j.jbmt.2008.03.005. Epub 2008 May 23.
Fascia provides mechanical support and frameworks for the other tissues of the body. Type 1 collagen is the major protein component of fascia, and fibroblasts are the cell type primarily responsible for its biosynthesis and remodeling. Research on fibroblasts interacting with collagen matrices provides new insights regarding how cell-matrix tension state and growth factor specificity regulate cell migration and matrix remodeling.
筋膜为身体的其他组织提供机械支撑和框架。I型胶原蛋白是筋膜的主要蛋白质成分,成纤维细胞是主要负责其生物合成和重塑的细胞类型。对成纤维细胞与胶原基质相互作用的研究为细胞-基质张力状态和生长因子特异性如何调节细胞迁移和基质重塑提供了新的见解。