额外的Y染色体短串联重复序列（Y-STR）基因座对解析常见单倍型和近亲个体的影响。
The impact of additional Y-STR loci on resolving common haplotypes and closely related individuals.
作者信息
Decker A E, Kline M C, Vallone P M, Butler J M
机构信息
National Institute of Standards and Technology, Biochemical Science Division, Gaithersburg, MD 20899, United States.
出版信息
Forensic Sci Int Genet. 2007 Jun;1(2):215-7. doi: 10.1016/j.fsigen.2007.01.012. Epub 2007 Feb 27.
Commercial Y-STR kits have permitted laboratories to go beyond the original nine minimal haplotype loci (MHL) and to discover the advantage of additional Y-STR loci in resolving common haplotypes. In an effort to examine the impact of Y-STR markers beyond the 17 loci now available in commercial kit form, new Y-STR loci are being investigated on a common set of samples representative of the major U.S. population groups. Additional Y-STRs can also increase the power of discrimination between closely related male individuals, which is important not only in forensics but also in the paternity and genetic genealogy communities.
商业化的Y染色体短串联重复序列（Y-STR）试剂盒使实验室能够超越最初的9个最小单倍型位点（MHL），并发现增加Y-STR位点在解析常见单倍型方面的优势。为了研究超出目前商业化试剂盒形式所包含的17个位点的Y-STR标记的影响，正在对一组代表美国主要人群组的常见样本进行新Y-STR位点的研究。额外的Y-STRs还可以增强对亲缘关系较近的男性个体的鉴别能力，这不仅在法医学中很重要，在亲子鉴定和遗传谱系研究领域也很重要。
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