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心脏CT:检测冠状动脉狭窄的先进技术。

Cardiac CT: state of the art for the detection of coronary arterial stenosis.

作者信息

Achenbach Stephan

机构信息

Department of Cardiology, University of Erlangen-Nürnberg, Ulmenweg 18, 91054 Erlangen, Germany.

出版信息

J Cardiovasc Comput Tomogr. 2007 Jul;1(1):3-20. doi: 10.1016/j.jcct.2007.04.007. Epub 2007 May 18.

Abstract

The recent evolution of multidetector computed tomography (CT) technology has substantially improved the ability of CT to visualize the heart and coronary arteries. After injection of contrast agent, relatively reliable imaging of the coronary arteries can be achieved, even though some restrictions are caused because the spatial and temporal resolutions are still somewhat limited. Several studies have shown that stenoses of the native coronary arteries can be detected with high sensitivity and specificity if image quality is adequate. More challenging situations include imaging of patients with stents and bypass grafts. Several clinical applications have been defined as "appropriate" and include the use of CT angiography in patients who have symptoms but who cannot exercise or who have an uninterpretable stress test result, or in patients with acute chest pain of intermediate likelihood for coronary artery disease but lack of electrocardiographic changes or myocardial enzyme elevations. It can be expected that further improvement of CT technology will help to more firmly establish the clinical role of CT coronary angiography and to explore further applications of this technique.

摘要

多排螺旋计算机断层扫描(CT)技术的最新进展已显著提高了CT对心脏和冠状动脉的可视化能力。注射造影剂后,即使由于空间和时间分辨率仍有一定限制而导致一些局限性,也能够实现相对可靠的冠状动脉成像。多项研究表明,如果图像质量足够,原生冠状动脉狭窄能够以高灵敏度和特异性被检测出来。更具挑战性的情况包括对有支架和搭桥移植的患者进行成像。一些临床应用已被定义为“合适的”,包括对有症状但无法运动或应激试验结果无法解读的患者,或对冠状动脉疾病可能性中等但缺乏心电图改变或心肌酶升高的急性胸痛患者使用CT血管造影。可以预期,CT技术的进一步改进将有助于更稳固地确立CT冠状动脉造影的临床作用,并探索该技术的更多应用。

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