资源匮乏的门诊环境中，HIV阳性女性行环形电外科切除术的结果。
Outcome of loop electrosurgical excision for HIV-positive women in a low-resource outpatient setting.
作者信息
Kietpeerakool Chumnan, Suprasert Prapaporn, Srisomboon Jatupol
机构信息
Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
出版信息
Int J Gynaecol Obstet. 2009 Apr;105(1):10-3. doi: 10.1016/j.ijgo.2008.11.006. Epub 2008 Dec 12.
OBJECTIVE
To assess outcome in HIV-positive women undergoing the loop electrosurgical excision procedure (LEEP).
METHOD
A prospective study was conducted with 789 outpatients undergoing LEEP at Chiang Mai University Hospital between October 2004 and June 2008.
RESULTS
The 70 HIV-positive women (8.9%) were younger (P<0.001) and had a lower parity (P<0.001) than the remaining women. The proportion of women undergoing LEEP for persistent low-grade lesions was higher (8.6% vs 1.9%) and the prevalence of margin involvement was higher (60.0% vs 49.4%) among the HIV-positive women. After adjusting for age, parity, menopausal status, size of excised lesion, and histopathologic result, HIV infection was not significantly associated with LEEP complications (adjusted odds ratio, 0.41; 95% confidence interval, 0.15-1.15).
CONCLUSION
The higher risk of resection margin involvement in HIV-infected women was not associated with LEEP complications.
目的
评估接受环形电切术（LEEP）的HIV阳性女性的治疗结果。
方法
对2004年10月至2008年6月期间在清迈大学医院接受LEEP的789例门诊患者进行了一项前瞻性研究。
结果
70例HIV阳性女性（8.9%）比其余女性更年轻（P<0.001）且产次更低（P<0.001）。接受LEEP治疗持续性低度病变的HIV阳性女性比例更高（8.6%对1.9%），切缘受累的发生率也更高（60.0%对49.4%）。在调整年龄、产次、绝经状态、切除病变大小和组织病理学结果后，HIV感染与LEEP并发症无显著相关性（调整后的优势比为0.41；95%置信区间为0.15-1.15）。
结论
HIV感染女性切缘受累风险较高与LEEP并发症无关。
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