Sutthichon Ponlawat, Kietpeerakool Chumnan
Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Asian Pac J Cancer Prev. 2009 Jul-Sep;10(3):351-4.
This study was conducted to evaluate the incidence and predictor of perioperative complications of the loop electrosurgical excision procedure (LEEP) in an outpatient setting at Chiang Mai University Hospital between October 2004 and December 2008. During this time period, 857 women were reviewed. Mean age was 45.1 years (range, 20-78 years). One-fourth of the women were postmenopausal. Eighty-one (9.5%) women were HIV positive. Perioperative complications were as follows: intraoperative bleeding, 29 (3.4%); early postoperative bleeding, 5 (0.6%); late postoperative bleeding, 42 (4.9%); and infection 37 (4.3%). The size of LEEP specimens was noted to be a significant predictor. Women who had a large LEEP specimen excised (defined as 20 mm or more) were 2.09 (95% Confidence Interval, 1.39-3.14) times more likely to have perioperative complications. In conclusion, outpatient LEEP is safe and has an acceptable perioperative complication rate, although large size carries greater risk.
本研究旨在评估2004年10月至2008年12月期间在清迈大学医院门诊进行的环形电切术（LEEP）围手术期并发症的发生率及预测因素。在此期间，对857名女性进行了评估。平均年龄为45.1岁（范围20 - 78岁）。四分之一的女性已绝经。81名（9.5%）女性HIV呈阳性。围手术期并发症如下：术中出血29例（3.4%）；术后早期出血5例（0.6%）；术后晚期出血42例（4.9%）；感染37例（4.3%）。LEEP标本大小是一个显著的预测因素。切除大的LEEP标本（定义为20毫米或更大）的女性发生围手术期并发症的可能性是2.09倍（95%置信区间，1.39 - 3.14）。总之，门诊LEEP是安全的，围手术期并发症发生率可接受，尽管标本大风险更高。
