Choi Charles T M, Hsu Chien-Hua
Department of Computer Science and Institute of Biomedical Engineering, National Chiao Tung University, 1001 Ta Hsueh Road, Hsin Chu 300, Taiwan, ROC.
Ann Biomed Eng. 2009 Mar;37(3):614-24. doi: 10.1007/s10439-008-9622-9. Epub 2008 Dec 16.
Simultaneous electrical stimulation of neighboring electrodes in cochlear prosthesis systems generates channel interaction. However, intermediate channels, or virtual channels between the neighboring electrodes can be created through controlled channel interaction. This effect may be exploited for sending new information to the hearing nerves by stimulating in a suitable manner. The actual stimulation sites are therefore not limited to the number of electrodes. Clinical experiments, however, show that virtual channels are not always perceived. In this paper, electrical simulation with finite element analysis on a half turn human cochlea model is adopted to model the virtual channel effect, and the conditions for generating virtual channels are discussed. Five input current ratios (100/0, 70/30, 50/50, 30/70, 0/100) are applied to generate virtual channels. Three electrode arrays parameters are taken into consideration: distance between electrode contact and modiolus, spacing between adjacent electrode contacts and scale of electrode contact size. By observing the activating function contours, the virtual channel patterns and performances can be measured and examined. The results showed that a broad excitation pattern is necessary to produce the kind of electrode interaction that can form distinct virtual channels.
人工耳蜗系统中相邻电极的同步电刺激会产生通道相互作用。然而,通过可控的通道相互作用,可以在相邻电极之间创建中间通道或虚拟通道。通过以合适的方式进行刺激,这种效应可被用于向听神经发送新信息。因此,实际的刺激位点不限于电极的数量。然而,临床实验表明,虚拟通道并非总能被感知到。本文采用对人半规管耳蜗模型进行有限元分析的电模拟方法来模拟虚拟通道效应,并讨论了产生虚拟通道的条件。应用五个输入电流比(100/0、70/30、50/50、30/70、0/100)来产生虚拟通道。考虑了三个电极阵列参数:电极触点与蜗轴之间的距离、相邻电极触点之间的间距以及电极触点尺寸的比例。通过观察激活函数等高线,可以测量和检验虚拟通道的模式和性能。结果表明,需要广泛的激发模式才能产生那种能够形成明显虚拟通道的电极相互作用。