江蓠化学成分的研究。

Studies on chemical constituents of Gracilaria verrucosa.

作者信息

Aydoğmuş Zeynep, Topcu Gülaçti, Güven Kasim Cemal

机构信息

Faculty of Pharmacy, Department of Analytical Chemistry, Istanbul University, Beyazit, Istanbul, Turkey.

出版信息

Nat Prod Res. 2008 Dec;22(18):1589-96. doi: 10.1080/14786410701838130.

DOI:10.1080/14786410701838130

PMID:19085413

Abstract

A new sterol glucoside, (24R)-5 alpha-stigmast-9-(11)-en-3beta-D-glucopyranoside (1) has been isolated from a methanol extract of the red alga Gracilaria verrucosa, while cholesterol and (Z)-9-hexadecenoic acid (palmitoleic acid) have been isolated from a dichloromethane-acetone extract of the same alga. Additionally, an oily fraction of a dichloromethane-acetone extract has been investigated by gas chromatography/mass spectrometry (GC/MS). The main components in the oily fraction were heneicosanoic acid (49.8%), (Z)-9-octadecenoic acid (15.8%), and 15-tetracosenoic acid (15.6%) in addition to a few hydrocarbons, simple aromatics and a new compound, namely 3,4-dimethyl-5-carboxyclic acid-1-oxacyclopent-3-en-2-one. The structures of the isolated compounds have been elucidated by spectroscopic methods.

摘要

从红藻江蓠的甲醇提取物中分离出一种新的甾醇葡萄糖苷，即(24R)-5α-豆甾-9(11)-烯-3β-D-葡萄糖苷(1)，同时从同一藻类的二氯甲烷-丙酮提取物中分离出胆固醇和(Z)-9-十六碳烯酸(棕榈油酸)。此外，还通过气相色谱/质谱联用(GC/MS)对二氯甲烷-丙酮提取物的油状部分进行了研究。除了一些烃类、简单芳烃和一种新化合物，即3,4-二甲基-5-羧酸-1-氧杂环戊-3-烯-2-酮外，油状部分的主要成分是二十一烷酸(49.8%)、(Z)-9-十八碳烯酸(15.8%)和15-二十四碳烯酸(15.6%)。通过光谱方法阐明了分离出的化合物的结构。