一种来自牡丹的吡咯衍生物。

A pyrrole derivative from Paeonia suffruticosa.

作者信息

Xiao K, Song Q-H, Zhang S-W, Xuan L-J

机构信息

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

出版信息

Nat Prod Res. 2008 Dec;22(18):1614-9. doi: 10.1080/14786410701855902.

DOI:10.1080/14786410701855902

PMID:19085417

Abstract

A new pyrrole derivative, 2-methyl-5-(2'-O-alpha-D-glucopyranosyl-1'-oxygen)-propylpyrrole, named paesuffrioside (1), was isolated from the water-soluble extract of the root cortex of Paeonia suffruticosa, together with 11 known compounds. Their structures were elucidated by spectroscopic analysis and chemical transformation. Compounds 2 and 3 were isolated from this plant for the first time.

摘要

从牡丹根皮的水溶性提取物中分离出一种新的吡咯衍生物，2-甲基-5-(2'-O-α-D-吡喃葡萄糖基-1'-氧)-丙基吡咯，命名为芍药苦苷（1），同时还分离出11种已知化合物。通过光谱分析和化学转化阐明了它们的结构。化合物2和3首次从该植物中分离得到。