Ekiert Halina, Klimek-Szczykutowicz Marta, Szopa Agnieszka
Chair and Department of Pharmaceutical Botany, Faculty of Pharmacy, Medical College, Jagiellonian University, Medyczna 9, 30-688 Kraków, Poland.
Department of Dermatology, Cosmetology and Aesthetic Surgery, The Institute of Medical Sciences, Medical College, Jan Kochanowski University, al. IX Wieków Kielc 19a, 25-516 Kielce, Poland.
Plants (Basel). 2022 Dec 5;11(23):3379. doi: 10.3390/plants11233379.
The aim of this review is to perform a systematic review of scientific papers and an in-depth analysis of the latest research related to Andrews as a valuable plant species, important in pharmacy and cosmetology. bark root- is a medicinal raw material formerly known from traditional Chinese medicine (TCM) but less common in official European medicine. It was introduced for the first time in the European Pharmacopoeia Supplement 9.4 in 2018. In this work, the numerous possible applications of this raw material were depicted based on modern professional pharmacological studies documenting its very valuable medicinal values, including antioxidant, cytoprotective, anti-cancer, anti-inflammatory, cardioprotective, anti-atherosclerotic, anti-diabetic and hepatoprotective activities. The scientific studies indicated that the profile of raw material activity is mainly due to paeonol, paeoniflorin and 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose. Moreover, the significance of this plant (its different organs) in the production of cosmetics was underlined. finds increasing application in cosmetology due to research on its chronic dermatitis, anti-aging and brightening effects. Furthermore, some biotechnological research has been described aimed at developing effective in vitro micropropagation protocols for
本综述的目的是对科学论文进行系统综述,并对与作为一种在药学和美容学中具有重要价值的植物物种—— Andrews 相关的最新研究进行深入分析。树皮根是一种曾在传统中药(TCM)中为人所知的药用原料,但在欧洲官方医学中不太常见。它于2018年首次被引入《欧洲药典增补本9.4》。在这项工作中,基于现代专业药理学研究描述了这种原料的众多可能应用,这些研究记录了其非常有价值的药用价值,包括抗氧化、细胞保护、抗癌、抗炎、心脏保护、抗动脉粥样硬化、抗糖尿病和肝脏保护活性。科学研究表明,原料活性特征主要归因于丹皮酚、芍药苷和1,2,3,4,6 - 五没食子酰基 - β - D - 吡喃葡萄糖。此外,强调了这种植物(其不同器官)在化妆品生产中的重要性。由于对其慢性皮炎、抗衰老和提亮效果的研究,它在美容学中的应用越来越广泛。此外,还描述了一些生物技术研究,旨在开发有效的体外微繁殖方案用于