Basu M, Duckett J R A, Papanikolaou N
Department of Obstetrics and Gynaecology, Medway Maritime Hospital, Gillingham, UK.
J Obstet Gynaecol. 2008 Nov;28(8):783-6. doi: 10.1080/01443610802431840.
The study aimed to assess the efficacy of retropubic urethrolysis (RU) on obstructive and overactive bladder (OAB) symptoms and to assess the effect on voiding parameters in a small series of six women. Each patient had significant obstructive or OAB symptoms, and was obstructed on urodynamics. RU was performed if conservative measures, anticholinergics and urethral dilatation failed. The mean time since colposuspension was 10 years. All patients complained of poor flow, with 5/6 complaining of OAB symptoms. Postoperatively, all the women reported improved voiding. The maximum flow rate increased from a mean of 11.2 ml/s to 16.4 ml/s, with the Pdet at a maximum flow decreasing from a mean of 43.2 cm H(2)O to 34.7 cm H(2)O. The post-void residual was less than 100 ml in all six patients postoperatively. One reported improved OAB symptoms. There are variable success rates for RU reported in the literature. Careful patient selection and counselling is necessary.
该研究旨在评估耻骨后尿道松解术（RU）对梗阻性和膀胱过度活动症（OAB）症状的疗效，并评估其对一小系列6名女性排尿参数的影响。每位患者均有明显的梗阻性或OAB症状，且尿动力学检查存在梗阻。若保守治疗、抗胆碱能药物治疗及尿道扩张均无效，则进行RU手术。距膀胱颈悬吊术的平均时间为10年。所有患者均主诉排尿困难，其中5/6患者伴有OAB症状。术后，所有女性均报告排尿情况改善。最大尿流率从平均11.2 ml/s增至16.4 ml/s，最大尿流率时的膀胱内压从平均43.2 cm H₂O降至34.7 cm H₂O。所有6例患者术后残余尿量均少于100 ml。1例报告OAB症状改善。文献报道RU的成功率各不相同。仔细选择患者并给予咨询很有必要。
