Tan Susanna, Tambar Siddharth, Chohan Saima, Ramsey-Goldman Rosalind, Lee Chin
Northwestern University, Feinberg School of Medicine, Division of Rheumatology, McGaw Pavilion, Chicago, IL 60611, USA.
J Clin Rheumatol. 2008 Dec;14(6):350-2. doi: 10.1097/rhu.0b013e31817de0fb.
We describe a case of an acute myocardial infarction (MI) coincident with correction of severe thrombocytopenia in a 23-year old African American woman with systemic lupus erythematosus (SLE) in the absence of coronary artery disease on angiography. Despite a history of anticardiolipin and beta(2)-glycoprotein I antibodies, she had no prior thromboembolic events. The occurrence of an acute MI after rapid normalization in the platelet count suggests the need for close monitoring of possible cardiovascular events during and after treatment of severe thrombocytopenia in the presence of antiphospholipid antibodies.
我们描述了一例23岁患有系统性红斑狼疮（SLE）的非裔美国女性，在血管造影显示无冠状动脉疾病的情况下，急性心肌梗死（MI）与严重血小板减少症的纠正同时发生。尽管有抗心磷脂和β2糖蛋白I抗体病史，但她既往无血栓栓塞事件。血小板计数迅速恢复正常后发生急性心肌梗死，提示在存在抗磷脂抗体的情况下，治疗严重血小板减少症期间及之后，需要密切监测可能发生的心血管事件。
