Castillo-Machalskis Isabel, D'Armas Haydelba, Malaver Nora, Núñez Maximiano
Instituto Oceanográfico de Venezuela, Universidad de Oriente (UDO-Sucre), Av. Universidad, Cerro Colorado, Código postal 6101, Cumaná, Venezuela.
Rev Biol Trop. 2007 Sep-Dec;55(3-4):761-5.
The antibacterial activity of marine fungi extracts was evaluated by a test of efficiency. The fungi were previously inoculated in Malt Agar (EMA) extract with 50% of seawater and growth for 60 days. Triplicate antibiograms were carried out with the extracts. An ANOVA I with a posteriori Duncan test were applied to the diameters of inhibition zones. The extracts of Aspergillus ochraceus 3MCMC3 and Penicillium citrinum (14) 4MCMC16 present wide spectral antibacterial properties, inhibiting 100% and 80% of the developing germs, especially Pseudomonas aeruginosa 9027. The extract of Penicillium (1) 3MLLC5 had the highest efficiency on this strain; P. aeruginosa 9027 and Escherichia coli 10536 were the most sensitive germs when treated with these extracts. These marine fungi can be an important source of antibacterial secondary metabolites.
通过效率测试评估了海洋真菌提取物的抗菌活性。真菌预先接种在含有50%海水的麦芽琼脂(EMA)提取物中,培养60天。对提取物进行了三次重复的抗菌谱测试。对抑菌圈直径应用了带有事后邓肯检验的单因素方差分析。赭曲霉3MCMC3和桔青霉(14)4MCMC16的提取物具有广泛的光谱抗菌特性,能抑制100%和80%的生长细菌,尤其是铜绿假单胞菌9027。青霉(1)3MLLC5的提取物对该菌株的效率最高;用这些提取物处理时,铜绿假单胞菌9027和大肠杆菌10536是最敏感的细菌。这些海洋真菌可能是抗菌次生代谢物的重要来源。