Xie Jing-jing, Zhao Jing, Li Shao-ping
Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Zhongguo Zhong Yao Za Zhi. 2008 Aug;33(16):1997-2001.
To predict the shelf life of Chinese Angelica by investigating the stability of its active components.
The classic homeothermia method was used for forecast the shelf life, and HPLC was applied for quantitative determination of chemical compounds in Chinese Angelica.
The correlation equations, thermal constant at ambient temperature (k(25 degrees C)) and shelf life (t(0.9)) for coniferyl ferulate and Z-Ligustilide were lgk = -5152. 1/T + 13.8 (r = 0.9985), 3. 33 x 10(-4), 13 d and lgk = -4064.6/T + 10.4 (r = 0.9997), 5.91 x 10(-4), 7 d, respectively.
The shelf life of Chinese Angelica has been established, which suggests that it is very important for ensuring the safety and efficacy of Chinese crude drug.
通过研究当归有效成分的稳定性来预测其保质期。
采用经典恒温法预测保质期，并用高效液相色谱法对当归中的化学成分进行定量测定。
阿魏酸松柏酯和Z-藁本内酯的相关方程、常温下的热常数（k(25℃)）和保质期（t(0.9)）分别为lgk = -5152. 1/T + 13.8（r = 0.9985），3. 33 x 10(-4)，13天和lgk = -4064.6/T + 10.4（r = 0.9997），5.91 x 10(-4)，7天。
已确定当归的保质期，这表明对于确保中药的安全性和有效性非常重要。
