一项比较H Pipelle与标准Pipelle在“无接触”（阴道镜）宫腔镜检查时进行子宫内膜取样的随机试验。

A randomised trial comparing the H Pipelle with the standard Pipelle for endometrial sampling at 'no-touch' (vaginoscopic) hysteroscopy.

作者信息

Madari S, Al-Shabibi N, Papalampros P, Papadimitriou A, Magos A

机构信息

University Department of Obstetrics and Gynaecology, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK.

出版信息

BJOG. 2009 Jan;116(1):32-7. doi: 10.1111/j.1471-0528.2008.01992.x.

DOI:10.1111/j.1471-0528.2008.01992.x

PMID:19087077

Abstract

OBJECTIVES

To evaluate the effectiveness and tolerance of H Pipelle compared with the standard Pipelle as an endometrial biopsy device at outpatient 'no-touch' hysteroscopy.

DESIGN

A prospective randomised trial carried out in an outpatient diagnostic hysteroscopy clinic.

SETTING

A large undergraduate teaching hospital.

POPULATION

Sixty women investigated for abnormal menstruation in an outpatient diagnostic hysteroscopy clinic.

METHODS

Prospective randomised trial comparing the H Pipelle with the standard Pipelle de Cornier.

MAIN OUTCOME MEASURES

Adequacy of the biopsy specimens and women's experience.

RESULTS

Ninety-three percent (H Pipelle) and 87% (Pipelle) of the biopsy specimens were judged to be adequate for histological diagnosis (P > 0.05). However, obtaining endometrial sampling with the H Pipelle was significantly quicker (median times: 39 seconds [H Pipelle] and 102 seconds [Pipelle], P < 0.0001) and less painful (median visual analogue scale score: 1 [H Pipelle] and 5 [Pipelle], P = 0.011).

CONCLUSIONS

The H Pipelle not only makes it possible to perform hysteroscopy and endometrial biopsy with minimal instrumentation but is also associated with a shorter biopsy time and less discomfort than the standard Pipelle without any loss of biopsy adequacy.

摘要

目的

评估在门诊“非接触式”宫腔镜检查中，与标准的 Pipelle 相比，H Pipelle 作为子宫内膜活检装置的有效性和耐受性。

设计

在门诊诊断性宫腔镜检查诊所进行的一项前瞻性随机试验。

地点

一家大型本科教学医院。

研究对象

在门诊诊断性宫腔镜检查诊所对 60 名月经异常的女性进行研究。

方法

前瞻性随机试验，比较 H Pipelle 与标准的 Pipelle de Cornier。

主要观察指标

活检标本的充足性和女性的体验。

结果

93%（H Pipelle）和 87%（Pipelle）的活检标本被判定足以进行组织学诊断（P>0.05）。然而，使用 H Pipelle 进行子宫内膜采样明显更快（中位时间：39 秒[H Pipelle]和 102 秒[Pipelle]，P<0.0001）且疼痛较轻（中位视觉模拟评分：1[H Pipelle]和 5[Pipelle]，P = 0.011）。