Madari S, Al-Shabibi N, Papalampros P, Papadimitriou A, Magos A
University Department of Obstetrics and Gynaecology, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK.
BJOG. 2009 Jan;116(1):32-7. doi: 10.1111/j.1471-0528.2008.01992.x.
To evaluate the effectiveness and tolerance of H Pipelle compared with the standard Pipelle as an endometrial biopsy device at outpatient 'no-touch' hysteroscopy.
A prospective randomised trial carried out in an outpatient diagnostic hysteroscopy clinic.
A large undergraduate teaching hospital.
Sixty women investigated for abnormal menstruation in an outpatient diagnostic hysteroscopy clinic.
Prospective randomised trial comparing the H Pipelle with the standard Pipelle de Cornier.
Adequacy of the biopsy specimens and women's experience.
Ninety-three percent (H Pipelle) and 87% (Pipelle) of the biopsy specimens were judged to be adequate for histological diagnosis (P > 0.05). However, obtaining endometrial sampling with the H Pipelle was significantly quicker (median times: 39 seconds [H Pipelle] and 102 seconds [Pipelle], P < 0.0001) and less painful (median visual analogue scale score: 1 [H Pipelle] and 5 [Pipelle], P = 0.011).
The H Pipelle not only makes it possible to perform hysteroscopy and endometrial biopsy with minimal instrumentation but is also associated with a shorter biopsy time and less discomfort than the standard Pipelle without any loss of biopsy adequacy.
评估在门诊“非接触式”宫腔镜检查中，与标准的 Pipelle 相比，H Pipelle 作为子宫内膜活检装置的有效性和耐受性。
在门诊诊断性宫腔镜检查诊所进行的一项前瞻性随机试验。
一家大型本科教学医院。
在门诊诊断性宫腔镜检查诊所对 60 名月经异常的女性进行研究。
前瞻性随机试验，比较 H Pipelle 与标准的 Pipelle de Cornier。
活检标本的充足性和女性的体验。
93%（H Pipelle）和 87%（Pipelle）的活检标本被判定足以进行组织学诊断（P>0.05）。然而，使用 H Pipelle 进行子宫内膜采样明显更快（中位时间：39 秒[H Pipelle]和 102 秒[Pipelle]，P<0.0001）且疼痛较轻（中位视觉模拟评分：1[H Pipelle]和 5[Pipelle]，P = 0.011）。
H Pipelle 不仅能够以最少的器械进行宫腔镜检查和子宫内膜活检，而且与标准 Pipelle 相比，活检时间更短，不适感更小，同时活检充足性没有任何损失。
