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肾上腺皮质病变的诊断方法。

A diagnostic approach to adrenal cortical lesions.

作者信息

McNicol Anne Marie

机构信息

Molecular and Cellular Pathology, School of Medicine, The University of Queensland, Brisbane, Australia.

出版信息

Endocr Pathol. 2008 Winter;19(4):241-51. doi: 10.1007/s12022-008-9055-x.

DOI:10.1007/s12022-008-9055-x
PMID:19089656
Abstract

The adrenal gland is not a common specimen in surgical pathology practice as, until recently, adrenal tumors were recognized in life only if associated with hypersecretion of hormones or evidence of malignancy. However, adrenal nodules are not uncommon at autopsy, and the number of these found in life is now increasing as they are identified when the abdomen is scanned for the investigation of other diseases using computed tomography or magnetic resonance imaging. It is therefore becoming increasingly important for the surgical pathologist to be aware of the range of pathology in the gland and to understand how to approach the specimens. This short review will deal with lesions of the adrenal cortex.

摘要

肾上腺并非外科病理学实践中的常见标本,因为直到最近,肾上腺肿瘤只有在伴有激素分泌过多或恶性证据时才会在生前被发现。然而,肾上腺结节在尸检中并不少见,而且随着使用计算机断层扫描或磁共振成像对腹部进行扫描以检查其他疾病时发现这些结节,其在生前被发现的数量正在增加。因此,外科病理学家了解肾上腺的病理学范围并懂得如何处理这些标本变得越来越重要。本简短综述将讨论肾上腺皮质的病变。

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2
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本文引用的文献

1
The prognostic value of two different histopathological scoring systems for adrenocortical carcinomas.两种不同组织病理学评分系统对肾上腺皮质癌的预后价值。
Histopathology. 2007 Aug;51(2):239-45. doi: 10.1111/j.1365-2559.2007.02747.x. Epub 2007 Jun 25.
2
Recent advances in histopathology and immunohistochemistry of adrenocortical carcinoma.肾上腺皮质癌组织病理学和免疫组织化学的最新进展
Endocr Pathol. 2006 Winter;17(4):345-54. doi: 10.1007/s12022-006-0006-0.
3
Adrenocortical tumorigenesis.肾上腺皮质肿瘤发生
Qatar Med J. 2013 Nov 1;2013(1):7-11. doi: 10.5339/qmj.2013.2. eCollection 2013.
4
Adrenocortical carcinoma and synchronous malignancies.肾上腺皮质癌和同时性恶性肿瘤。
J Cancer. 2010 Aug 12;1:108-11. doi: 10.7150/jca.1.108.
Ann N Y Acad Sci. 2006 Nov;1088:319-34. doi: 10.1196/annals.1366.001.
4
Adrenal myelolipomas show nonrandom X-chromosome inactivation in hematopoietic elements and fat: support for a clonal origin of myelolipomas.肾上腺髓脂肪瘤在造血成分和脂肪中显示出非随机的X染色体失活:支持髓脂肪瘤的克隆起源。
Am J Surg Pathol. 2006 Jul;30(7):838-43. doi: 10.1097/01.pas.0000202044.05333.17.
5
Prevalence of adrenal incidentaloma in a contemporary computerized tomography series.当代计算机断层扫描系列中肾上腺偶发瘤的患病率。
J Endocrinol Invest. 2006 Apr;29(4):298-302. doi: 10.1007/BF03344099.
6
Aberrant expression of human luteinizing hormone receptor by adrenocortical cells is sufficient to provoke both hyperplasia and Cushing's syndrome features.肾上腺皮质细胞中人类促黄体生成素受体的异常表达足以引发增生和库欣综合征特征。
J Clin Endocrinol Metab. 2006 Jan;91(1):196-203. doi: 10.1210/jc.2005-1975. Epub 2005 Oct 25.
7
Adrenal incidentalomas -- a continuing management dilemma.肾上腺偶发瘤——持续存在的管理难题。
Endocr Relat Cancer. 2005 Sep;12(3):585-98. doi: 10.1677/erc.1.00951.
8
Aberrant expression of hormone receptors in adrenal Cushing's syndrome.肾上腺库欣综合征中激素受体的异常表达。
Pituitary. 2004;7(4):225-35. doi: 10.1007/s11102-005-1083-7.
9
Congenital adrenal hyperplasia.先天性肾上腺增生症
Lancet. 2005;365(9477):2125-36. doi: 10.1016/S0140-6736(05)66736-0.
10
Gene expression profiling of human adrenocortical tumors using complementary deoxyribonucleic Acid microarrays identifies several candidate genes as markers of malignancy.使用互补脱氧核糖核酸微阵列对人类肾上腺皮质肿瘤进行基因表达谱分析,确定了几个候选基因作为恶性肿瘤的标志物。
J Clin Endocrinol Metab. 2005 Mar;90(3):1819-29. doi: 10.1210/jc.2004-1075. Epub 2004 Dec 21.