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输尿管再植术后出现膀胱憩室的儿童的尿动力学检查结果及功能性或解剖性梗阻情况

Urodynamic findings and functional or anatomical obstructions in children who developed bladder diverticula after reimplantation of the ureter.

作者信息

Tilanus Martijn, Klijn Aart, Dik Pieter, de Kort Laetitia, de Jong Tom

机构信息

University Children's Hospital UMC Utrecht, Pediatric Renal Center, Utrecht, The Netherlands.

出版信息

Neurourol Urodyn. 2009;28(3):241-5. doi: 10.1002/nau.20629.

Abstract

OBJECTIVE

To study the clinical and urodynamic parameters of children who developed bladder diverticula (BD) after ureteral reimplantation.

MATERIALS AND METHODS

We have reviewed records of 15 children who underwent ureteric reimplantation, possibly with diverticulectomy between January 1998 and October 2004, who postoperatively developed BD and compared the results with 25 patients, surgically treated for primary vesicoureteric reflux (VUR) without BD development after reimplantation. A total of 737 reimplantations was performed in 492 patients. Of the 15 patients and 25 controls we reviewed voiding history and free uroflowmetry, urodynamic parameters, findings on urethrocystoscopy, VCUG and signs of dysfunctional or anatomical obstruction.

RESULTS

Of the fifteen patients with a postoperative diverticulum, one patient (7%) had an infravesical obstruction in combination with a normal voiding pattern, nine patients (60%) had severe dysfunctional voiding and two patients (13%) had both. Three patients had no infravesical obstruction nor dysfunctional voiding. Urodynamically the mean Pmax postoperatively was 96.8 (cm-H(2)O) in the obstructed patients (BD-group) (in controls 50.0 cm-H(2)O) and 95.6 (cm-H(2)O) for the dysfunctional voiders (in controls 61.8 cm-H(2)O). The difference between the Pmax values of BD-group and controls was significant on the 95% C.I. (P < 0.01).

CONCLUSION

Dysfunctional voiding and infravesical obstruction in children appear to be important risk factors for acquired BD. Voiding pressures are significantly higher in patients that developed BD. Cognitive bladder training to normalize voiding pressures should be done before surgery if feasible. Special attention should be paid to the persistence of an infravesical obstruction.

摘要

目的

研究输尿管再植术后发生膀胱憩室(BD)患儿的临床及尿动力学参数。

材料与方法

我们回顾了1998年1月至2004年10月期间接受输尿管再植术(可能同时行憩室切除术)且术后发生BD的15例患儿的记录,并将结果与25例因原发性膀胱输尿管反流(VUR)接受手术治疗且再植术后未发生BD的患者进行比较。492例患者共进行了737次再植术。我们对15例患者和25例对照者的排尿史、自由尿流率、尿动力学参数、尿道膀胱镜检查结果、排尿性膀胱尿道造影(VCUG)以及功能障碍或解剖性梗阻的体征进行了回顾。

结果

在15例术后出现憩室的患者中,1例(7%)存在膀胱下梗阻且排尿模式正常,9例(60%)有严重的功能性排尿障碍,2例(13%)两者兼有。3例患者既无膀胱下梗阻也无功能性排尿障碍。尿动力学检查显示,梗阻患者(BD组)术后平均最大排尿压(Pmax)为96.8(cm-H₂O)(对照组为50.0 cm-H₂O),功能性排尿障碍患者为95.6(cm-H₂O)(对照组为61.8 cm-H₂O)。BD组与对照组的Pmax值在95%置信区间上差异有统计学意义(P < 0.01)。

结论

儿童功能性排尿障碍和膀胱下梗阻似乎是后天性BD的重要危险因素。发生BD的患者排尿压力明显更高。如果可行,术前应进行认知膀胱训练以使排尿压力正常化。应特别注意膀胱下梗阻的持续存在。

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