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先天性心脏手术后的体外膜肺氧合循环支持

Extracorporeal membrane oxygenation circulatory support after congenital cardiac surgery.

作者信息

Suzuki Yasuyuki, Yamauchi Sanae, Daitoku Kazuyuki, Fukui Kozo, Fukuda Ikou

机构信息

Department of Thoracic and Cardiovascular Surgery, Hirosaki University School of Medicine, Hirosaki, Aomori, Japan.

出版信息

ASAIO J. 2009 Jan-Feb;55(1):53-7. doi: 10.1097/MAT.0b013e31818f0056.

Abstract

Extracorporeal membrane oxygenation (ECMO) is widely used for circulatory support in pediatric cardiac patients with low cardiac output and hypoxemia after cardiac surgery. We evaluated retrospectively, the efficacy of postoperative ECMO support following congenital cardiac surgery in our hospital. From April 2002 to February 2008, seven patients (median age 30 months) received postoperative mechanical support. Three had complete repair including Fontan circulation and four had palliative repair. In four patients, ECMO was initiated in the operating room, in three patients in the intensive care unit, postoperatively. Of the seven patients, one died on ECMO (support withdrawn), one died shortly after ECMO was discontinued, and five were successfully weaned and survived to hospital discharge. One of the survivors died 4 months after the operation due to pneumonia and septic shock. The mean duration of ECMO support was 121 hours (in survivors). During ECMO, the major complication was bleeding, despite adequate control of activated clotting time. We conclude that ECMO support for heart failure and respiratory insufficiency after congenital cardiac surgery was effective, and the result of ECMO support for respiratory insufficiency was better than for heart failure.

摘要

体外膜肺氧合(ECMO)广泛应用于心脏手术后心输出量低和低氧血症的小儿心脏患者的循环支持。我们回顾性评估了我院先天性心脏手术后ECMO支持的疗效。2002年4月至2008年2月,7例患者(中位年龄30个月)接受了术后机械支持。3例进行了包括Fontan循环在内的完全修复,4例进行了姑息性修复。4例患者在手术室开始使用ECMO,3例患者在术后重症监护病房开始使用。7例患者中,1例在ECMO上死亡(停止支持),1例在ECMO停止后不久死亡,5例成功撤机并存活至出院。1例幸存者在术后4个月因肺炎和感染性休克死亡。ECMO支持的平均持续时间为121小时(幸存者)。在ECMO期间,尽管活化凝血时间得到了充分控制,但主要并发症是出血。我们得出结论,ECMO对先天性心脏手术后心力衰竭和呼吸功能不全的支持是有效的,并且ECMO对呼吸功能不全的支持结果优于心力衰竭。

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