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长期使用后6%过氧化氢牙齿美白凝胶对牙釉质微硬度的评估。

Evaluation of a 6% hydrogen peroxide tooth-whitening gel on enamel microhardness after extended use.

作者信息

Toteda Mariarosaria, Philpotts Carole J, Cox Trevor F, Joiner Andrew

机构信息

Unilever Oral Care, Bebington, Wirral, UK.

出版信息

Quintessence Int. 2008 Nov;39(10):853-8.

Abstract

OBJECTIVES

To evaluate the effects of a 6% hydrogen peroxide tooth whitener, Xtra White, on sound human enamel microhardness in vitro after an extended and exaggerated simulated 8 weeks of product use.

METHOD AND MATERIALS

Polished human enamel specimens were prepared and baseline microhardness and color measurements determined. The enamel specimens were exposed to a fluoride-containing toothpaste for 30 seconds and then exposed to water, Xtra White, a control carbopol gel containing no hydrogen peroxide, or a carbonated beverage (each group, n = 8) for 20 minutes. Specimens were exposed to whole saliva at all other times. In order to simulate 8 weeks of extended product use, quadruple the length of the manufacturer's instructions, 112 treatments, were conducted. Microhardness measurements were taken after 2, 4, 6, and 8 weeks of simulated treatments, and color was measured after 2 and 8 weeks.

RESULTS

The Xtra White-treated specimens showed a statistically significant (P < .0001) increase in L* and decrease in b* compared to the water-treated specimens after 2 weeks simulated use, indicating bleaching had occurred. The carbonated beverage-treated specimens were significantly softened (P = .0009) compared to baseline after only 1 treatment. The carbopol gel-treated specimens were significantly softened (P = .0028) after 2 weeks of simulated treatments compared to baseline. There were no statistically significant differences in enamel microhardness between baseline and all treatment times for XW and water groups.

CONCLUSION

Xtra White does not have any deleterious effects on sound human enamel microhardness after an extended and exaggerated simulated 8 weeks of product use.

摘要

目的

评估一款6%过氧化氢牙齿美白剂Xtra White,在经过延长且夸张的模拟8周产品使用后,对健康人牙釉质体外显微硬度的影响。

方法与材料

制备经过抛光的人牙釉质样本,并测定基线显微硬度和颜色。牙釉质样本先接触含氟牙膏30秒,然后分别接触水、Xtra White、不含过氧化氢的对照卡波姆凝胶或碳酸饮料(每组n = 8)20分钟。其他时间样本均接触全唾液。为模拟8周的延长产品使用,按照制造商说明的四倍时长进行了112次处理。在模拟处理2、4、6和8周后进行显微硬度测量,在2周和8周后测量颜色。

结果

与经过2周模拟使用的水处理样本相比,使用Xtra White处理的样本在L值上有统计学显著增加(P < .0001),b值下降,表明发生了漂白。仅经过1次处理后,与基线相比,碳酸饮料处理的样本显著软化(P = .0009)。与基线相比,经过2周模拟处理后,卡波姆凝胶处理的样本显著软化(P = .0028)。XW组和水组在基线和所有处理时间的牙釉质显微硬度上无统计学显著差异。

结论

在经过延长且夸张的模拟8周产品使用后,Xtra White对健康人牙釉质显微硬度没有任何有害影响。

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