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使用钆布醇在1.5T和3T场强下进行心肌延迟强化磁共振成像的个体内比较。

Intraindividual comparison of myocardial delayed enhancement MR imaging using gadobenate dimeglumine at 1.5 T and 3 T.

作者信息

Klumpp Bernhard D, Sandstede Joern, Lodemann Klaus P, Seeger Achim, Hoevelborn Tobias, Fenchel Michael, Kramer Ulrich, Claussen Claus D, Miller Stephan

机构信息

Department for Diagnostic Radiology, Eberhard Karls University Tuebingen, Hoppe-Seyler-Str. 3, 72076 Tuebingen, Germany.

出版信息

Eur Radiol. 2009 May;19(5):1124-31. doi: 10.1007/s00330-008-1248-7. Epub 2008 Dec 18.

Abstract

For contrast-enhanced imaging techniques relying on strong T1 weighting, 3 T provides increased contrast compared with 1.5 T. The aim of our study was the intraindividual comparison of delayed enhancement MR imaging at 1.5 T and at 3 T. Twenty patients with myocardial infarction were examined at 1.5 T and 3 T. Fifteen minutes after injection of contrast agent (0.1 mmol gadobenate dimeglumine per kg body weight), inversion recovery gradient recalled echo (IR-GRE) sequences were acquired (1.5 T/3 T: TR 11.0/9.9 ms, TE 4.4/4.9 ms, flip 30 degrees /30 degrees , slice thickness 6/6 mm) to assess myocardial viability. Two observers rated image quality (Wilcoxon signed rank test). Quantification of hyperenhanced myocardium and standardized SNR/CNR measurements were performed (Student's t test). There was no significant difference with respect to image quality (1.5 T/3 T: 3.5/3.3, p = 0.34, reader 1; 2.4/2.7, p = 0.12, reader 2) and infarction size (760 +/- 566/828 +/- 677 mm(2) at 1.5 T, 808 +/- 639/826 +/- 726 mm(2) at 3 T, reader 1/reader 2, p > 0.05). Mean SNR in hyperenhanced/normal myocardium was 19.2/6.2 at 1.5 T and 29.5/8.8 at 3 T (p < 0.05). Mean CNR was 14.3 at 1.5 T and 26.0 at 3 T (p < 0.05). Delayed enhancement MR imaging at 3 T is a robust procedure yielding superior tissue contrast at 3 T compared with 1.5 T which is, however, not reflected by increased image quality.

摘要

对于依赖强T1加权的对比增强成像技术,与1.5T相比,3T能提供更高的对比度。我们研究的目的是对1.5T和3T下的延迟增强磁共振成像进行个体内比较。20例心肌梗死患者分别在1.5T和3T下接受检查。注射造影剂(每千克体重0.1mmol钆贝葡胺)15分钟后,采集反转恢复梯度回波(IR-GRE)序列(1.5T/3T:重复时间11.0/9.9毫秒,回波时间4.4/4.9毫秒,翻转角30度/30度,层厚6/6毫米)以评估心肌活力。两名观察者对图像质量进行评分(Wilcoxon符号秩检验)。对心肌强化区域进行定量分析,并进行标准化信噪比/对比噪声比测量(Student's t检验)。图像质量方面无显著差异(1.5T/3T:3.5/3.3,p = 0.34,观察者1;2.4/2.7,p = 0.

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