Department of Internal Medicine, State Hospital, 25200 Erzurum, Turkey.
Dig Dis Sci. 2009 Dec;54(12):2629-33. doi: 10.1007/s10620-008-0647-6.
The Eastern Anatolia Region of Turkey is an endemic upper gastrointestinal (esophageal and gastric) cancer region, and the incidence of these cancers are still increasing in the region. We investigated demographic features, dietary habits, and some possible etiologic factors for this high prevalence. Special attention was given to the relationship between consumption of boiled yellow butter and the occurrence of gastric cancer. Age, sex, residential area, socio-economical status, educational status, vegetable and fruit consumption, alcohol and tobacco use, tea consumption, boiled butter usage, cooking and storage methods of the patients with gastric cancer and controls were investigated in East Anatolian Regional Erzurum State Hospital. Helicobacter pylori infection for gastric cancer risk was not studied. Fruit, yellow-green vegetables, boiled butter, and breads baked by animal manure consumptions and no refrigeration are found to be statistically significant etiologic factors for gastric carcinogenesis. Dietary habits might be risk factors for gastric carcinogenesis among East Anatolian population. Some regional differences in food processing and preparation also seem to play a role in gastric carcinogenesis.
土耳其东安纳托利亚地区是上消化道(食管和胃)癌症的地方性高发地区,该地区的癌症发病率仍在上升。我们研究了该地区的人口统计学特征、饮食习惯以及一些可能的病因因素。特别关注了食用煮黄奶油与胃癌发生之间的关系。在东安纳托利亚地区埃尔祖鲁姆州立医院,我们调查了胃癌患者和对照组的年龄、性别、居住地区、社会经济地位、教育程度、蔬菜和水果摄入、酒精和烟草使用、茶饮用、煮黄奶油使用、烹饪和储存方法。未研究幽门螺杆菌感染与胃癌风险的关系。水果、黄绿蔬菜、煮黄奶油、动物粪便烤制的面包和不冷藏被认为是胃癌发生的统计学显著病因因素。饮食习惯可能是东安纳托利亚人群胃癌发生的危险因素。一些地区在食品加工和准备方面的差异似乎也在胃癌发生中起作用。