Oguntibeju O O, van den Heever W M J, Van Schalkwyk F E
School of Health Technology, Central University of Technology, Free State, Bloemfontein, South Africa.
Pak J Biol Sci. 2007 Dec 15;10(24):4327-38. doi: 10.3923/pjbs.2007.4327.4338.
Available scientific evidence has revealed that macronutrients and micronutrients are critical for fighting HIV-infection, because they are required by the immune system and major organs to attack infectious pathogens, HIV inclusive. It is believed that weight gain or maintenance might be achieved through good nutrition and has helped to reduce the consequences of wasting in people living with HIV/AIDS. Nutrition has helped to strengthen the immune system and reduce the severity and impact of opportunistic infections in people living with HIV/AIDS. It is known that an immune dysfunction as a result of HIV/AIDS leads to malnutrition and this in turn leads to further immune dysfunction. Various research studies have confirmed that nutrient deficiencies are associated with immune dysfunction and accelerated progression to AIDS. In this review, the interrelationship between nutrition and immune system in HIV infection is presented.
现有科学证据表明,大量营养素和微量营养素对于对抗艾滋病毒感染至关重要,因为免疫系统和主要器官需要它们来攻击包括艾滋病毒在内的传染性病原体。人们认为,通过良好的营养可以实现体重增加或维持体重,这有助于减轻艾滋病毒/艾滋病感染者消瘦的后果。营养有助于增强免疫系统,减轻艾滋病毒/艾滋病感染者机会性感染的严重程度和影响。众所周知,艾滋病毒/艾滋病导致的免疫功能障碍会导致营养不良,而这反过来又会导致进一步的免疫功能障碍。各种研究证实,营养缺乏与免疫功能障碍以及艾滋病进展加速有关。在本综述中,阐述了艾滋病毒感染中营养与免疫系统之间的相互关系。