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年轻个体舌部神经鞘瘤累及舌后外侧缘:病例报告

Lingual schwannoma involving the posterior lateral border of the tongue in a young individual: case report.

作者信息

Pereira Luciano José, Pereira Patrícia Peres Iucif, dos Santos João de Paula, Reis Filho Viator Ferreira, Dominguete Paulo Roberto, Pereira Alessandro A Costa

机构信息

Clinical Dentistry Program, Vale do Rio Verde University - Oral Diagnosis Area - Três Corações-Minas Gerais, Brasil.

出版信息

J Clin Pediatr Dent. 2008 Fall;33(1):59-62. doi: 10.17796/jcpd.33.1.h131208u28306576.

Abstract

A schwannoma, also called neurilemmoma, is a benign, encapsulated, slow growing tumor arising from the neural sheath's Schwann cells of the peripheral, cranial or autonomic nerves. The etiology is unknown, there is no gender preference and the tumors occur most commonly between the ages of 20 and 50 years. Approximately 25-48% of these tumors occur in the head and neck region, with only 1% occurring in the mouth. The current case reports a schwannoma of the tongue, found in a 12 year-old boy. The lesion was present for 6 months. The clinical examination revealed a 1.5x1.0 cm, sessile, rubbery, non-tender non-ulcerated mass on the right posterior lateral border of the tongue. An excisional biopsy was performed under local anesthesia. The histological sections showed a circumscribed submucosal nodule composed of spindle cells with thin wavy nuclei arranged as typical Antoni A (with Verocay bodies) and Antoni B areas. Nuclear palisading distribution (typical of a schwannoma) was readily identifiable. The patient was recurrence free after one year.

摘要

施万细胞瘤,也称为神经鞘瘤,是一种良性、有包膜、生长缓慢的肿瘤,起源于外周神经、颅神经或自主神经的神经鞘雪旺细胞。病因不明,无性别倾向,肿瘤最常发生于20至50岁之间。这些肿瘤约25% - 48%发生在头颈部区域,仅1%发生在口腔。本病例报告了一名12岁男孩舌部的施万细胞瘤。该病变已存在6个月。临床检查发现舌右侧后外侧缘有一个1.5×1.0厘米、无柄、橡皮样、无压痛、未溃疡的肿块。在局部麻醉下进行了切除活检。组织学切片显示一个边界清楚的黏膜下结节,由梭形细胞组成,细胞核薄且呈波浪状,排列成典型的Antoni A区(有Verocay小体)和Antoni B区。核栅栏状分布(施万细胞瘤的典型表现)易于识别。患者一年后无复发。

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