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儿童舌部神经鞘瘤。

Schwannoma of the tongue in a child.

机构信息

Department of Maxillofacial Surgery, University of Zagreb School of Medicine, University Hospital Dubrava, Avenue Gojko Susak 6, 10000 Zagreb, Croatia.

出版信息

J Craniomaxillofac Surg. 2011 Sep;39(6):441-4. doi: 10.1016/j.jcms.2010.10.004. Epub 2010 Oct 30.

DOI:10.1016/j.jcms.2010.10.004
PMID:21041099
Abstract

A schwannoma or neurilemmoma is a benign, slow growing, usually solitary and encapsulated tumour originating from Schwann cells of the nerve sheath. Approximately 25-40% of all schwannomas are seen in the soft tissues of the head and neck, often originate from the acoustic nerve. Intraoral schwannomas are rare and account for 1% of schwannomas of the head and neck region. We report the case of a 10-year-old boy diagnosed with a schwannoma of the tongue. The purpose of this report is to emphasize the possibility of diagnosing schwannoma among all other lingual lesions in children. The disease itself was diagnosed histologically after complete surgical excision. Five years after surgical treatment, the patient is without signs of recurrence. This paper highlights the importance of a multidisciplinary approach in the diagnosis and surgical treatment of this very rare entity.

摘要

神经鞘瘤或雪旺细胞瘤是一种良性、生长缓慢的肿瘤,通常为单发、有包膜,起源于神经鞘的施万细胞。大约 25-40%的神经鞘瘤发生于头颈部的软组织,常起源于听神经。口腔内神经鞘瘤罕见,占头颈部神经鞘瘤的 1%。我们报告了一例 10 岁男孩舌部神经鞘瘤的病例。本报告的目的是强调在所有其他儿童舌部病变中诊断神经鞘瘤的可能性。该疾病通过完全手术切除后组织学确诊。手术治疗 5 年后,患者无复发迹象。本文强调了在这种非常罕见的实体的诊断和手术治疗中采用多学科方法的重要性。

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Schwannoma of the tongue in a child.儿童舌部神经鞘瘤。
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Diagnosis and management of hypoglossal nerve-derived schwannoma in the floor of mouth: a case series.舌下神经管源性神经鞘瘤的诊断与治疗:病例系列。
BMC Oral Health. 2022 Jun 29;22(1):265. doi: 10.1186/s12903-022-02302-2.
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Deletion of Nf2 in neural crest-derived tongue mesenchyme alters tongue shape and size, Hippo signalling and cell proliferation in a region- and stage-specific manner.
神经嵴来源的舌间质中 NF2 的缺失以区域和阶段特异性的方式改变舌的形状和大小、 Hippo 信号传导和细胞增殖。
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