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癌症免疫疗法的最新进展,重点是疫苗。

Recent advances in cancer immunotherapy with an emphasis on vaccines.

作者信息

Cavallo Federica, Forni Guido

机构信息

Molecular Biotechnology Center, Department of Clinical and Biological Sciences, University of Torino, Via Nizza, 52 I-10126 Torino, Italy.

出版信息

Expert Rev Vaccines. 2009 Jan;8(1):25-8. doi: 10.1586/14760584.8.1.25.

Abstract

Recent Advances in Cancer Immunotherapy with an Emphasis on Vaccines was the first meeting organized by the European Society of Cancer Immunology and Immunotherapy and Progress in Vaccine against Cancer, in collaboration with the Institute of Biological Research and Biotechnology of the National Hellenic Research Foundation, in a joint effort towards the setting up of a new generation of cancer vaccines. The main topics of the meeting included: the role of the tumor microenvironment in protecting the tumor from immune attack; differences in immunotherapy outcome in hematological malignancies versus solid tumors; rationale of multi-epitope vaccines; Treg cell elimination/inactivation, tumor stroma destruction, angiogenesis inhibition and the potentiality of 'preventive' vaccination in breast, colon, prostate and ovarian cancer in the early stages and during the 'wait-and-see' period. The ninth Progress in Vaccines against Cancer meeting will be held in Sofia, Bulgaria, 8-10 October 2009, at the Hilton Hotel.

摘要

《癌症免疫疗法最新进展:聚焦疫苗》是由欧洲癌症免疫与免疫疗法协会以及抗癌疫苗进展组织的首次会议,此次会议与希腊国家研究基金会生物研究与生物技术研究所合作,共同致力于研发新一代癌症疫苗。会议的主要议题包括:肿瘤微环境在保护肿瘤免受免疫攻击中的作用;血液系统恶性肿瘤与实体瘤免疫治疗效果的差异;多表位疫苗的原理;调节性T细胞的清除/失活、肿瘤基质破坏、血管生成抑制以及在乳腺癌、结肠癌、前列腺癌和卵巢癌早期及“观察等待”期进行“预防性”疫苗接种的潜力。第九届抗癌疫苗进展会议将于2009年10月8日至10日在保加利亚索非亚的希尔顿酒店举行。

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