Department of Infectious Diseases, University of Iceland Medical School, Reykjavik, Iceland.
Acta Ophthalmol. 2010 May;88(3):367-70. doi: 10.1111/j.1755-3768.2008.01367.x. Epub 2008 Dec 13.
This study aimed to study the incidence and clinical characteristics of patients diagnosed with actinomycotic canaliculitis in Iceland.
We present a nationwide, retrospective case series for which cases were identified by searches of hospital diagnostic registries and pathology databases. Case histories were reviewed and histopathological analysis repeated to confirm the diagnosis.
Nine cases of actinomycotic canaliculitis were diagnosed in Iceland during 1988-2007. Subjects included six women and three men and represented 16% of all patients diagnosed with actinomycosis in the country. The incidence was 0.16 cases/100 000 inhabitants/year. Age-specific incidence rates were 0.59 cases/100 000 inhabitants/year for the 40-59-year-old age group and 1.37 cases/100 000 inhabitants/year for individuals aged 60-79 years. All patients underwent a three-way snip procedure and 1 week of topical antibacterial therapy.
Actinomycotic canaliculitis is an uncommon condition which frequently eludes diagnosis. Topical antibiotics for 1 week may be sufficient following surgery, a finding which contrasts with previous reports.
本研究旨在研究冰岛确诊放线菌性泪小管炎患者的发病率和临床特征。
我们进行了一项全国性的回顾性病例系列研究，通过医院诊断登记处和病理数据库搜索来确定病例。对病例进行了回顾，并进行了组织病理学分析以确认诊断。
1988-2007 年期间，冰岛共确诊了 9 例放线菌性泪小管炎患者。患者包括 6 名女性和 3 名男性，占该国所有放线菌病患者的 16%。发病率为 0.16 例/10 万居民/年。40-59 岁年龄组的特定年龄发病率为 0.59 例/10 万居民/年，60-79 岁年龄组的发病率为 1.37 例/10 万居民/年。所有患者均接受了三通式活检术和 1 周的局部抗菌治疗。
放线菌性泪小管炎是一种罕见的疾病，常被漏诊。手术后使用 1 周的局部抗生素可能就足够了，这与之前的报告结果不同。
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