Xiang Shengjin, Lin Bin, Pan Qintuo, Zheng Meiqin, Qin Xiaoyi, Wang Youpei, Zhang Zongduan
Eye Hospital of Wenzhou Medical University, Wenzhou Department of Ophthalmology, the Second Hospital of Yinzhou, Ningbo, China.
Medicine (Baltimore). 2017 Mar;96(9):e6188. doi: 10.1097/MD.0000000000006188.
The purpose of our study is to analyze the clinical, ultrasonic, microbiologic, and histopathologic characteristics, management, and outcomes in a series of primary canaliculitis with concretions patients who underwent canaliculotomy with curettage.Thirty-six patients were reviewed for age, sex, location and laterality, duration of symptoms, clinical symptoms, ultrasonic signs, result of microbiologic culture and histopathologic examination, treatment, and outcomes. Main outcomes were the clinical, ultrasonic, and microbiological characteristics of the canalicular concretions; the histopathologic profiles; and the treatment effect.Thirty-six patients were identified with concretions in all 37 cases of the patients with canaliculitis. There were 30 (83.3%) female patients with a mean age of 54.2 years. Twenty-eight (77.8%) patients were misdiagnosed or delayed diagnosed, and the mean duration was 17.1 months. The common most clinical presentations were discharge (100%), epiphora (66.7%), erythema (52.8%), and swelling (47.2%), and concretions were found in 31 of 37 patients by typical clinical manifestations and in 5 of 6 patients by ultrasonic. Actinomyces was found in 8 of 13 histopathologic specimens, and microbiological cultures were positive in 13 of 24 patients. All patients underwent canaliculotomy with curettage to completely remove all concretions and contents; 35 of 36 patients' symptoms improved and 1 recurred after treatment at a median of 21.7 months follow-up according to the telephonic questionnaires.Canalicular concretions play an important role in primary canaliculitis. Canaliculotomy with curettage is a standard therapy with canalicular concretions, and the surgical removal of all possible concretions is essential for cure.
我们研究的目的是分析一系列接受泪小管切开刮除术的原发性泪小管炎伴结石患者的临床、超声、微生物学和组织病理学特征、治疗方法及预后。回顾了36例患者的年龄、性别、病变位置及单侧或双侧情况、症状持续时间、临床症状、超声征象、微生物培养结果及组织病理学检查结果、治疗方法及预后。主要观察指标为泪小管结石的临床、超声和微生物学特征;组织病理学特征;以及治疗效果。在37例泪小管炎患者中,36例患者被确诊有结石。女性患者30例(83.3%),平均年龄54.2岁。28例(77.8%)患者被误诊或延误诊断,平均延误时间为17.1个月。最常见的临床表现为溢脓(100%)、流泪(66.7%)、红斑(52.8%)和肿胀(47.2%),37例患者中有31例通过典型临床表现发现结石,6例患者中有5例通过超声发现结石。13例组织病理学标本中有8例发现放线菌,24例患者中有13例微生物培养呈阳性。所有患者均接受泪小管切开刮除术以彻底清除所有结石及内容物;根据电话问卷调查,36例患者中有35例症状改善,1例在中位随访21.7个月后复发。泪小管结石在原发性泪小管炎中起重要作用。泪小管切开刮除术是治疗泪小管结石的标准疗法,彻底清除所有可能的结石对治愈至关重要。