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全膝关节置换术后健康结局的传统评估受到反应转移现象的干扰。

Traditional assessment of health outcome following total knee arthroplasty was confounded by response shift phenomenon.

作者信息

Razmjou Helen, Schwartz Carolyn E, Yee Albert, Finkelstein Joel A

机构信息

Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room MG301, Toronto, ON, Canada.

出版信息

J Clin Epidemiol. 2009 Jan;62(1):91-6. doi: 10.1016/j.jclinepi.2008.08.004.

Abstract

OBJECTIVES

To examine the existence, direction, and effect of response shift as measured by the total score of Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and SF-36 physical and mental component score domains at 6 months and 1 year after primary total knee arthroplasty (TKA).

STUDY DESIGN AND SETTING

Consecutive candidates participated in the study. In line with the Then-test design, two sets of questionnaires were completed at 6 months and 1 year postoperatively. Patients were divided into three groups on the basis of minimal clinically important differences (MCIDs). Parametric and nonparametric statistics and generalized mixed effects models were used.

RESULTS

Two hundred and thirty-six patients completed the study. The magnitude of response shift increased over time for SF-36 physical and mental component scores. The traditional unadjusted presurgical and 1-year postsurgical assessment failed to reveal any mental health improvement, whereas the adjusted treatment effect demonstrated statistically significant changes.

CONCLUSION

Response shift phenomenon increases with time in patients undergoing orthopedic interventions. The traditional pre- and post-assessment of joint replacement surgery may be confounded by a change in perspective and in internal standards of measurement in patients undergoing surgery. Response shift has substantial impact on measuring recovery in this population.

摘要

目的

通过西安大略和麦克马斯特大学骨关节炎指数(WOMAC)总分以及全膝关节置换术(TKA)后6个月和1年时SF - 36身体和心理成分得分域来检查反应转移的存在、方向和影响。

研究设计与设置

连续的候选者参与了该研究。根据Then检验设计,在术后6个月和1年完成了两组问卷。患者根据最小临床重要差异(MCID)分为三组。使用了参数和非参数统计以及广义混合效应模型。

结果

236名患者完成了研究。SF - 36身体和心理成分得分的反应转移幅度随时间增加。传统的未调整术前和术后1年评估未显示任何心理健康改善,而调整后的治疗效果显示出统计学上的显著变化。

结论

接受骨科干预的患者中反应转移现象随时间增加。关节置换手术的传统术前和术后评估可能会因手术患者的视角变化和内部测量标准变化而混淆。反应转移对该人群恢复的测量有重大影响。

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