Duntze J, Litré C-F, Bajolet O, Theret E, Eap C, Peruzzi P, Rousseaux P
Service de neurochirurgie, hôpital Maison-Blanche, 45, rue Cognacq-Jay, 51092 Reims cedex, France.
Neurochirurgie. 2009 Dec;55(6):569-72. doi: 10.1016/j.neuchi.2008.10.010. Epub 2008 Dec 17.
Clostridium perfringens is rare in neurosurgery. The source of clostridial brain abscess is usually a penetrating head injury. We report the case of a 57-year-old man who had parietal glioblastoma resection with local carmustine chemotherapy and who presented a clostridial brain abscess three weeks later. Progression was especially brutal, leading to patient's death in few hours. We discuss the etiology and progression of this case compared to the data reported in the literature.
产气荚膜梭菌在神经外科手术中较为罕见。梭菌性脑脓肿的来源通常是穿透性头部损伤。我们报告了一例57岁男性患者，该患者接受了顶叶胶质母细胞瘤切除术并进行了局部卡莫司汀化疗，三周后出现了梭菌性脑脓肿。病情进展极为迅速，导致患者在数小时内死亡。我们将结合文献报道的数据讨论该病例的病因及病情进展。
