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胶质母细胞瘤伴瘤内脓肿形成。病例报告。

Glioblastoma associated with intratumoral abscess formation. Case report.

作者信息

Tsugu Atsushi, Osada Takahiro, Nishiyama Jun, Matsumae Mitsunori

机构信息

Department of Neurosurgery, Tokai University School of Medicine, Isehara, Kanagawa.

出版信息

Neurol Med Chir (Tokyo). 2012;52(2):99-102. doi: 10.2176/nmc.52.99.

Abstract

A 45-year-old man presented with a rare case of glioblastoma associated with intratumoral abscess formation manifesting as headache and vomiting after an appendectomy. Computed tomography and magnetic resonance imaging demonstrated a ring-enhanced lesion mimicking malignant glioma. Craniotomy and tumor removal were performed. Abscess formation within the intra-axial tumor was found intraoperatively. Histological examination revealed glioblastoma with abscess, and the etiological agent was anaerobic Gram-negative bacilli. The suspected route of microbial migration and colonization in this tumor was bacteremia from appendicitis.

摘要

一名45岁男性患者,出现了罕见的胶质母细胞瘤合并瘤内脓肿形成的病例,表现为阑尾切除术后头痛和呕吐。计算机断层扫描和磁共振成像显示一个环形强化病变,类似恶性胶质瘤。进行了开颅手术并切除肿瘤。术中发现轴内肿瘤内有脓肿形成。组织学检查显示为胶质母细胞瘤合并脓肿,病原体为厌氧革兰氏阴性杆菌。该肿瘤中微生物迁移和定植的可疑途径是阑尾炎引起的菌血症。

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