Tsugu Atsushi, Osada Takahiro, Nishiyama Jun, Matsumae Mitsunori
Department of Neurosurgery, Tokai University School of Medicine, Isehara, Kanagawa.
Neurol Med Chir (Tokyo). 2012;52(2):99-102. doi: 10.2176/nmc.52.99.
A 45-year-old man presented with a rare case of glioblastoma associated with intratumoral abscess formation manifesting as headache and vomiting after an appendectomy. Computed tomography and magnetic resonance imaging demonstrated a ring-enhanced lesion mimicking malignant glioma. Craniotomy and tumor removal were performed. Abscess formation within the intra-axial tumor was found intraoperatively. Histological examination revealed glioblastoma with abscess, and the etiological agent was anaerobic Gram-negative bacilli. The suspected route of microbial migration and colonization in this tumor was bacteremia from appendicitis.
一名45岁男性患者,出现了罕见的胶质母细胞瘤合并瘤内脓肿形成的病例,表现为阑尾切除术后头痛和呕吐。计算机断层扫描和磁共振成像显示一个环形强化病变,类似恶性胶质瘤。进行了开颅手术并切除肿瘤。术中发现轴内肿瘤内有脓肿形成。组织学检查显示为胶质母细胞瘤合并脓肿,病原体为厌氧革兰氏阴性杆菌。该肿瘤中微生物迁移和定植的可疑途径是阑尾炎引起的菌血症。